Allergic Contact Dermatitis Due to Wool Fat and Cholesterol

Diagnosis and Prevalence of Lanolin Allergy

“…Consistent with past studies, 9–15 the highest reaction rates in our study occurred with lanolin alcohol derivatives, which suggests that the alcoholic fraction may be the component causing the allergic reaction. In addition, our results indicate that lanolin allergy is dependent on not only the derivative of lanolin but also the manufacturer.…”

Untoward Response With Topical Fluorouracil

“…The information I have at the present time on the absorption spectrum for 5-fluorouracil ( Figure) does not make it appear that it would be subject to phototoxic or photoaller-gic response from sun exposure, according to a written communicaton from W. M. Sams, Jr. (May 10,1967). The most likely expla¬ nation for the discomfort which occurs on exposure to the sun is not difficult to under¬ stand.…”

Periorbital Allergic Contact Dermatitis Caused by Lanolin in a Lubricating Eye Ointment

“…4 Cases of ACD to lanolin in cosmetics and topical medicaments, but not ophthalmic agents, have been reported. 5,6 Ours is the first clearly defined case of lanolin in an ophthalmological medication causing periorbital ACD. The literature includes several large cohorts of patients with periorbital ACD, where lanolin derivatives are included in a long list of contact allergens.…”

“…4 Auto-inflammatory diseases are characterised by periodic or intermittent fevers and severe, localised inflammation in the absence of infectious or autoimmune aetiology. 5 Recent expanded definitions of HS include conditions without fever and with persistent inflammation and dysregulation of the innate immune system. 5 The commonality between all these conditions is the dysregulation of the inflammasone.…”