Allergic Acute Coronary Syndrome (Kounis Syndrome)

Memon, Sarfaraz; Chhabra, Lovely; Masrur, Shihab; Parker, Matthew W.

doi:10.1080/08998280.2015.11929274

Cited by 42 publications

(34 citation statements)

References 9 publications

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“…Tajda Keber et al [9] suggested measuring cardiac enzymes in acute allergic reaction patients as necessary to diagnose Kounis syndrome promptly and manage cardiac injury early and appropriately. Echocardiography and coronary angiography can provide detailed information to rule out takotsubo cardiomyopathy or other cardiac disorders in cardiac wall motion abnormalities patients [10]. Keita Goto et al [11] reported that thallium-201 (Tl) single-photon emission CT (SPECT) and 125I-15-(p-iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP) SPECT were conducted in a post-Kounis syndrome patient, and they revealed a local perfusion defect with decreased BMIPP uptake.…”

Section: Discussionmentioning

confidence: 99%

Contrast Media Induced Kounis Syndrome: A Case Report

et al. 2019

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Kounis syndrome is a rare anaphylactic reaction leading to coronary spasm, acute plaque rupture, or intrastent stenosis. Many types of medicine or environmental factors can potentially trigger Kounis syndrome by mast cell allergic reactions. In severe Kounis syndrome, reduced blood pressure or cardiac arrest may be accompanying symptoms. The treatment strategy for Kounis syndrome is usually difficult due to both cardiac dysfunction and allergic reactions. The delay to intervention to break the vicious circle may cause catastrophic complications. Therefore, early diagnosis is critical for physicians to outline detailed etiology for prevention and treat the cardiac and allergic symptoms in a timely manner. Here, we describe a case presenting rare severe Kounis syndrome with cardiac arrest which occurred after the administration of a contrast media.

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Section: Discussionmentioning

confidence: 99%

Contrast Media Induced Kounis Syndrome: A Case Report

et al. 2019

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“…Epinephrine, which is used routinely for the treatment of anaphylaxis, should also be cautiously used, because it may potentially worsen coronary vasospasm and aggravate coronary ischemia in KS. 12 ORCID…”

Section: Discussionmentioning

confidence: 99%

Kounis syndrome secondary to gadolinium contrast agent

Abusnina

Shehata

Abouzid

et al. 2019

Baylor University Medical Center Proceedings

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Cases of coronary artery spasm secondary to contrast agent use are rarely reported. Herein, we report the case of a 53-year-old woman who developed chest pain, dyspnea, and bradycardia and quickly become unresponsive after magnetic resonance imaging of the brain. A heart monitor showed ST elevation, and an electrocardiogram showed ST elevations in leads II, III, aVF, V3, and V4 and ST segment depression in lead I. Urgent left heart catheterization revealed no evidence of obstructive coronary artery disease or pulmonary embolism. A few days later, she was discharged from the hospital with no symptoms. A type I variant of Kounis syndrome was diagnosed.

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“…The exact role of allergy in cardiovascular disease is not clear and needs more investigations. Some studies have shown the role of allergy and allergic acute coronary syndrome (Kounis syndrome) in patients with ischemic heart disease [20,21]. Recently a population-based, matched cohort study showed that patients with previously diagnosed allergic rhinitis had significantly lower risk for myocardial infarction (P < 0.001) [22].…”

Section: Discussionmentioning

confidence: 99%