All-arthroscopic AMIC procedure for repair of cartilage defects of the knee

Abstract

PurposeBone marrow mesenchymal stem cells were introduced into clinical practice due to their ability to differentiate into many types of cells. Autologous matrix-induced chondrogenesis (AMIC) combines the microfracture method with matrix-based techniques that utilizes a collagen membrane to serve as a scaffold for new bone marrow mesenchymal stem cells, allowing effective reconstruction of even large fragments of a damaged cartilage surface.MethodsAll-arthroscopic technique to repair knee cartilage defects using the AMIC technique, which includes the use of a collagen matrix (porcine collagen type I and III) and fibrin glue—technique presentation.ConclusionThis technical note introduces an all-arthroscopic AMIC technique to reconstruct extensive cartilage defects (without bone defects). The technique may be used for treatment of all location of knee cartilage lesions.Level of evidenceV.

Arthroscopic Treatment of Chondral and Osteochondral Defects in the Ankle Using the Autologous Matrix-Induced Chondrogenesis Technique

“…A similar modification has been successfully used and applied by us previously. 13 Preliminary results of treatment with this technique provide hope for its wider use in the future. However, further research to prove the effectiveness of this method is required.…”

Dry Arthroscopy With a Retraction System for Matrix-Aided Cartilage Repair of Patellar Lesions

“…A mandatory prerequisite for such a procedure is equilibration of the joint pressure with atmospheric pressure. 5 Substituting gas for saline solution is an alternative to create a fluidfree environment but has been criticized because of the increased risk of gas-induced vascular embolization. Another issue is the constant outflow of gas, which complicates the insertion of the matrix.…”

Arthroscopic Technique for the Treatment of Patellar Chondral Lesions With the Patient in the Supine Position

“…5 Autologous chondrocyte implant techniques are effective treatments for chondral and osteochondral lesions, 15 but the use of these matrixes in a single procedure has facilitated the arthroscopic application of both the MACI 6,7,9 and AMIC techniques. 10 There are very few reports on the treatment of patellar lesions using these techniques arthroscopically. 12,13,16 The main difficulty when dealing with patellar chondral lesions arthroscopically is the inability to approach the articular surface perpendicularly.…”

“…9 Both techniques have been used for the treatment of femoral condylar [6][7][8][9] or, less frequently, tibial plateau lesions. 10 There are very few reports on the treatment of patellar lesions using these techniques arthroscopically. [11][12][13] We describe an arthroscopic approach to the patella with the patient lying in the supine position.…”