Alkali Retinopathy

Indocyanine Green Angiographic Features in a Case of Alkali Retinopathy

“…3 Fortunately, in our patient, visual acuity was not compromised by the alkali retinopathy. However, it is likely that alkali retinopathy could permanently limit visual recovery if the immediate or late complications of posterior segment inflammation, necrosis, neovascularization, or retinal detachment involve the macula.…”

“…2 In each of these patients, an alkali tablet was lodged in the cul de sac, resulting in superficial scleral necrosis and retinal necrosis or whitening. 2,3 In our patient, retinopathy may have been prevented by immediate copious irrigation of the eye and removal of any chemical remnant lodged in the fornices.…”

Indocyanine Green Angiographic Features in a Case of Alkali Retinopathy

“…3 Fortunately, in our patient, visual acuity was not compromised by the alkali retinopathy. However, it is likely that alkali retinopathy could permanently limit visual recovery if the immediate or late complications of posterior segment inflammation, necrosis, neovascularization, or retinal detachment involve the macula.…”

“…2 In each of these patients, an alkali tablet was lodged in the cul de sac, resulting in superficial scleral necrosis and retinal necrosis or whitening. 2,3 In our patient, retinopathy may have been prevented by immediate copious irrigation of the eye and removal of any chemical remnant lodged in the fornices.…”

Mechanisms of Retinal Damage after Ocular Alkali Burns

“…Alkali burns of the anterior segment can cause damage not only to the cornea but also result in widespread damage to the retina with later optic nerve pallor and glaucomatous cupping developing in severe cases. 21 This was recently documented in a clinical study of 28 patient eyes with corneal blindness from alkali burns, who subsequently underwent implantation of a Boston keratoprosthesis, allowing a clear view of the retina. 8 Most of these patients had glaucoma before Boston keratoprosthesis implantation or exhibited de novo glaucoma after Boston keratoprosthesis implantation.…”

Expanding the Spectrum of Alkali Retinopathy: Maculopathy following Alkali Burn

“…The focus is (initially) mainly on the anterior segment as corneal opacification precludes a detailed posterior segment examination. Only a few cases of alkali retinopathy have been described [ 3 , 6 ]. Several mechanisms have been suggested for posterior segment damage and persistent visual loss following alkali ocular burn.…”

“…Second, a direct penetration of the alkalic component through the sclera to involve both the choroid and the retina is suggested by the sharp localization of the retinopathy just internal to the obvious external burn in 3 previous reported patients with alkali retinopathy. In these patients, ocular penetration induced an ischemic necrosis not only of the conjunctiva and sclera but also of the choroid and retina [ 3 , 6 ]. Remarkably, in our patient, retinal damage was limited to the macular region, extending to the inferonasal part of the posterior pole.…”

Indocyanine Green Angiographic Features in a Case of Alkali Retinopathy

“…3 Fortunately, in our patient, visual acuity was not compromised by the alkali retinopathy. However, it is likely that alkali retinopathy could permanently limit visual recovery if the immediate or late complications of posterior segment inflammation, necrosis, neovascularization, or retinal detachment involve the macula.…”

“…2 In each of these patients, an alkali tablet was lodged in the cul de sac, resulting in superficial scleral necrosis and retinal necrosis or whitening. 2,3 In our patient, retinopathy may have been prevented by immediate copious irrigation of the eye and removal of any chemical remnant lodged in the fornices.…”

Mechanisms of Retinal Damage after Ocular Alkali Burns

“…Alkali burns of the anterior segment can cause damage not only to the cornea but also result in widespread damage to the retina with later optic nerve pallor and glaucomatous cupping developing in severe cases. 21 This was recently documented in a clinical study of 28 patient eyes with corneal blindness from alkali burns, who subsequently underwent implantation of a Boston keratoprosthesis, allowing a clear view of the retina. 8 Most of these patients had glaucoma before Boston keratoprosthesis implantation or exhibited de novo glaucoma after Boston keratoprosthesis implantation.…”

Expanding the Spectrum of Alkali Retinopathy: Maculopathy following Alkali Burn

“…The focus is (initially) mainly on the anterior segment as corneal opacification precludes a detailed posterior segment examination. Only a few cases of alkali retinopathy have been described [ 3 , 6 ]. Several mechanisms have been suggested for posterior segment damage and persistent visual loss following alkali ocular burn.…”

“…Second, a direct penetration of the alkalic component through the sclera to involve both the choroid and the retina is suggested by the sharp localization of the retinopathy just internal to the obvious external burn in 3 previous reported patients with alkali retinopathy. In these patients, ocular penetration induced an ischemic necrosis not only of the conjunctiva and sclera but also of the choroid and retina [ 3 , 6 ]. Remarkably, in our patient, retinal damage was limited to the macular region, extending to the inferonasal part of the posterior pole.…”

Indocyanine Green Angiographic Features in a Case of Alkali Retinopathy

“…3 Fortunately, in our patient, visual acuity was not compromised by the alkali retinopathy. However, it is likely that alkali retinopathy could permanently limit visual recovery if the immediate or late complications of posterior segment inflammation, necrosis, neovascularization, or retinal detachment involve the macula.…”

“…2 In each of these patients, an alkali tablet was lodged in the cul de sac, resulting in superficial scleral necrosis and retinal necrosis or whitening. 2,3 In our patient, retinopathy may have been prevented by immediate copious irrigation of the eye and removal of any chemical remnant lodged in the fornices.…”

Mechanisms of Retinal Damage after Ocular Alkali Burns

“…Alkali burns of the anterior segment can cause damage not only to the cornea but also result in widespread damage to the retina with later optic nerve pallor and glaucomatous cupping developing in severe cases. 21 This was recently documented in a clinical study of 28 patient eyes with corneal blindness from alkali burns, who subsequently underwent implantation of a Boston keratoprosthesis, allowing a clear view of the retina. 8 Most of these patients had glaucoma before Boston keratoprosthesis implantation or exhibited de novo glaucoma after Boston keratoprosthesis implantation.…”

Expanding the Spectrum of Alkali Retinopathy: Maculopathy following Alkali Burn

“…The focus is (initially) mainly on the anterior segment as corneal opacification precludes a detailed posterior segment examination. Only a few cases of alkali retinopathy have been described [ 3 , 6 ]. Several mechanisms have been suggested for posterior segment damage and persistent visual loss following alkali ocular burn.…”

“…Second, a direct penetration of the alkalic component through the sclera to involve both the choroid and the retina is suggested by the sharp localization of the retinopathy just internal to the obvious external burn in 3 previous reported patients with alkali retinopathy. In these patients, ocular penetration induced an ischemic necrosis not only of the conjunctiva and sclera but also of the choroid and retina [ 3 , 6 ]. Remarkably, in our patient, retinal damage was limited to the macular region, extending to the inferonasal part of the posterior pole.…”