Alfentanil infusions. Comparison of bolus administration of fentanyl with three alfentanil infusion regimens

Abstract

SummaryThree different dosage regimens of alfentanil were compared with boluses of fentanyl in 80 patients who underwent a variety of surgical procedures. Alfentanil given by infusion at a rate of 7.5 μg/kg/minute for 10 minutes followed by 0.75 μg/kg/minute, was shown to provide a stable anaesthetic which minimises the use of a volatile agent for surgery that lasts more than 45 minutes.