Aktivitas Antibakteri Ekstrak Batang Kecombrang (Etlingera elatior (Jack) R.M.Sm.) Terhadap Bakteri Plak Gigi Streptococcus mutans

Suryani, Nani; Nurjanah, Devi; Indriatmoko, Dimas Danang

doi:10.26874/jkk.v2i1.19

Cited by 20 publications

(21 citation statements)

References 6 publications

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“…Saponins diffuse through the outer membrane and vulnerable cell walls and then bind to the cytoplasmic membrane and cause cytoplasmic components to leak and result in cell lysis. 21,22 When the bacterial wall is not perfectly shaped and is damaged, the next secondary active substance, namely flavonoids, will easily enter into the cell, the cellular part of the bacteria and damage the bacterial nucleus. 16 The mechanism of action of flavonoids as antibacterial agents against Streptococcus mutans bacteria works by inhibiting the function of bacterial cell membranes, namely binding to bacterial cell membranes and forming complex compound bonds with soluble extracellular proteins so that the integrity of bacterial cell membranes is disrupted followed by the release of intracellular compounds.…”

Section: Discussionmentioning

confidence: 99%

ANTIBACTERIAL EFFECTIVENESS OF Stenochlaena palustris LEAVES EXTRACT AGAINST THE GROWTH OF Streptococcus mutans

Novita¹,

Firdaus²,

Taufiqurrahman³

2022

Dentino

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Background: Dental caries is a common chronic infectious disease of dental hard tissue resulting from the interaction between tooth structure, the microbial biofilm formed on the tooth surface, dietary as well as salivary influences. Streptococcus mutans are considered to be the main bacteria that play role in the formation of cariogenic biofilms. Chlorhexidine gluconate 0,2% is a commonly used mouthwash and considered as the gold standard. The long-term use of chlorhexidine gluconate 0,2% may cause side effects so an alternative mouthwash with natural ingredients is needed. Kelakai leaves extract contains bioactive compounds which has antimicrobial effects such as flavonoids, alkaloids, tannins and saponins which can be used as an alternative mouthwash for chlorhexidine gluconate 0.2%. Objective: The purpose of this study was to observe the antibacterial effectiveness of kelakai leaves extract with concentrations of 3.125%, 6.25%, 12.5%, 25%, 50%, 75% and 100% with chlorhexidine gluconate 0.2% on growth of Streptococcus mutans bacteria. Methods: This study conducted through true experimental laboratories with a post-test only research design with control group design. This study used 9 treatments with 5 repetitions so that there were a total of 45 samples. The treatment group was kelakai leaves extract with concentrations of 3.125%, 6.25%, 12.5%, 25%, 50%, 75% and 100% with two control groups namely chlorhexidine gluconate 0.2% and distilled water against Streptococcus mutans. Results: The MIC of kelakai leaves extract was set at a concentration of 12.5% and the MBC at a concentration of 50%. Conclusion: Kelakai leaves extract concentrations 50%, 75% and 100% has antibacterial effectiveness which equivalent to chlorhexidine gluconate 0,2% against Streptococcus mutans bacteria.Keywords: Antibacterial, Stenochlaena palustris leaves extract, Streptococcus mutans

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Section: Discussionmentioning

confidence: 99%

ANTIBACTERIAL EFFECTIVENESS OF Stenochlaena palustris LEAVES EXTRACT AGAINST THE GROWTH OF Streptococcus mutans

Novita¹,

Firdaus²,

Taufiqurrahman³

2022

Dentino

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“…Pareng is one of the traditional medicine made from a decoction of young stems of E. elatior which is used as a post-circumcision wound cleanser by the Gayo tribal community to prevent infection. The use of macerated stem as a wound cleanser is related to the content of secondary metabolites in E. elatior namely flavonoids (Lim 2014), antibacterial (Suryani et al 2019), and antimicrobial activity (Soemarie et al 2019). Several research mentions the use of macerated stem in traditional medicine to treat infections, digestive system disorders (Phumthum et al 2018), worm infections, abdominal pain, and anemia (Samarang et al 2015).…”

Section: Parengmentioning

confidence: 99%

Ethnobotanical knowledge of Etlingera elatior for medicinal and food uses among ethnic groups in Aceh Province, Indonesia

Saudah

ZUMAIDAR²,

Darusman³

et al. 2022

Biodiversitas

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Abstract. Saudah, Zumaidar, Darusman, Fitmawati, Roslim DI, Ernilasari. 2022. Ethnobotanical knowledge of Etlingera elatior for medicinal and food uses among ethnic groups in Aceh Province, Indonesia. Biodiversitas 23: 4361-4370. The tribes in Aceh Province have been using Etlingera elatior for various medicinal purposes and as a spice in their culinary. Nonetheless, detailed information on the uses of E. elatior among communities in Aceh is lacking. Therefore, this research aimed to explore the ethnobotanical knowledge among local tribes in Aceh regarding the uses of E. elatior for food and medicine. This research was conducted on eight ethnic groups in Aceh Province (i.e., Acehnese, Gayo, Alas, Aneuk Jamee, Kluet, Tamiang, Singkil, and Simeulue). The data collection was carried out by using semi-structured interviews and field observation. A total of 240 respondents (135 male and 105 female) were selected purposively to obtain local knowledge on the uses, processing techniques and modes of application of E. elatior for medicinal and food purposes. Descriptive statistics were used to analyze the data to determine the level of knowledge and plant parts used, both measured in fidelity level (FL). The results showed that men, elderly people and farmers had more knowledge about the uses of E. elatior as medicine and food ingredients. Traditional medicines made from this herb were used to cure coughs, sprains, postpartum and earaches. Makjun sejuk, pareng, lampok and tapal were the concoction used in traditional medicine. Stem and fruit were the most commonly used plant parts for medicinal herbs, while pounding was the most common processing technique followed by squeezing and grinding either singly or in a mixture used by drinking and rubbing. The uses of E. elatior in food were found in several local dishes with the most common use in a curry called Pliék U. Flower buds and fruit was the most commonly used part in food ingredients. Despite the unique and high uses of E. elatior among tribes in Aceh, the gap in knowledge, especially between the older and younger generations, might impact the loss of local wisdom regarding the plant.

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“…Penghambatan bakteri oleh tanin yaitu dengan menghambat enzim reverse transkriptase dan DNA topoisomerasi yang menyebabkan sel bakteri gagal terbentuk. Senyawa tanin juga dapat mengakibatkan kurang sempurnanya pembentukan dinding sel bakteri karena polipeptida dinding sel bakteri dirusak oleh tanin, sehingga sel bakteri akan lisis dan terjadi kematian bakteri (Suryani 2019).…”

Section: Skrining Fitokimia Ekstrak Etanolik Daun Binahongunclassified

Antibacterial Activity of Ethanolic Extract, n-Hexane Fraction, and Chloroform Fraction of Binahong Leaves (Anredera Cordifolia) on Escherichia Coli and its Phytochemical Screening

Pratiwi¹,

Mardiyaningsih

Ismiyati

et al. 2021

J Jamu Indo

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Binahong leaves (Anredera cordifolia (Ten.) Steenis) are known to contain antibacterial activity compounds. The compounds contained in binahong leaves include flavonoids, alkaloids, saponins, and tannins. Escherichia coli is a gram-negative bacteria that often causes infections such as diarrhea. The purpose of this study was to determine the effect of ethanolic extract, n-hexane fraction, and chloroform fraction of binahong leaves on the growth of Escherichia coli bacteria and its phytochemical screening This research used ethanolic extract, hexane fraction and chloroform fraction of binahong leaves against Escherichia coli bacteria with concentrations of 12.5, 25 and 50% The positive control was chloramphenicol and the negative control was DMSO The method used disk diffusion technique, marked the presence of clear areas around the paper disc that showed an obstacle to bacterial growth phytochemical screening of alkaloids, flavonoids, saponins and tannins using a test tube. The result showed antibacterial activity against the growth of Escherichia coli with the diameter of the inhibition zone at concentrations of 12.5, 25, and 50%, namely the hexane fraction of 8.16; 9.73 and 12.93 mm. At the chloroform fraction 7.67; 8.47 and 9.87 mm. and the ethanolic extract of 7.33; 9.95 and 13.32 mm. The result of the largest inhibition zone was the ethanolic extract of binahong leaves with a concentration of 50%. The results of phytochemical screening using a test tube showed that the compounds contained in the ethanolic extract were flavonoids, alkaloids, saponins, and tannins.

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Aktivitas Antibakteri Ekstrak Batang Kecombrang (Etlingera elatior (Jack) R.M.Sm.) Terhadap Bakteri Plak Gigi Streptococcus mutans

Cited by 20 publications

References 6 publications

ANTIBACTERIAL EFFECTIVENESS OF Stenochlaena palustris LEAVES EXTRACT AGAINST THE GROWTH OF Streptococcus mutans

ANTIBACTERIAL EFFECTIVENESS OF Stenochlaena palustris LEAVES EXTRACT AGAINST THE GROWTH OF Streptococcus mutans

Ethnobotanical knowledge of Etlingera elatior for medicinal and food uses among ethnic groups in Aceh Province, Indonesia

Antibacterial Activity of Ethanolic Extract, n-Hexane Fraction, and Chloroform Fraction of Binahong Leaves (Anredera Cordifolia) on Escherichia Coli and its Phytochemical Screening

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