Akne und Rosazea

Plewig, Gerd

doi:10.1007/3-540-26624-0_61

Cited by 7 publications

(4 citation statements)

References 47 publications

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“…When suspecting doping acne, drug‐induced acneiform exanthemas, especially due to halogens, B vitamins, lithium salts, isoniazid, glucocorticosteroids or tetracyclines, should be considered as a differential diagnosis. They are usually monomorphous consisting of follicular papules and pustules and lacking primary comedos [77].…”

Section: Clinical Features Of Doping Acnementioning

confidence: 99%

Abuse of anabolic‐androgenic steroids and bodybuilding acne: an underestimated health problem

Melnik

Jansen²,

Grabbe³

2007

J Deutsche Derma Gesell

116

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Abuse of anabolic-androgenic steroids (AAS) by members of fitness centers and others in Germany has reached alarming dimensions. The health care system provides the illegal AAS to 48.1 % of abusers. Physicians are involved in illegal prescription of AAS and monitoring of 32.1 % of AAS abusers. Besides health-threatening cardiovascular, hepatotoxic and psychiatric long-term side effects of AAS, acne occurs in about 50 % of AAS abusers and is an important clinical indicator of AAS abuse, especially in young men 18-26 years of age. Both acne conglobata and acne fulminans can be induced by AAS abuse. The dermatologist should recognize bodybuilding acne, address the AAS abuse, and warn the patient about other potential hazards.

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Section: Clinical Features Of Doping Acnementioning

confidence: 99%

Abuse of anabolic‐androgenic steroids and bodybuilding acne: an underestimated health problem

Melnik

Jansen²,

Grabbe³

2007

J Deutsche Derma Gesell

116

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“…Guidelines recommend giving doxycycline 50‐100 mg twice daily [1], along with proper eyelid hygiene and the use of lubricants [4]. Isotretinoin does not relieve the symptoms of ocular rosacea [5]. An interdisciplinary collaboration between dermatologists and ophthalmologists appears important.…”

Section: Introductionmentioning

confidence: 99%

Treatment of ocular rosacea with 40 mg doxycycline in a slow release form

Pfeffer

Borelli

Zierhut

et al. 2011

J Deutsche Derma Gesell

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“…B. Malassezia, Demodex). gramnegativer Rosazea sowie M. Morbihan in Einzelfällen eine Behandlung mit 10-20 mg Isotretinoin täg-lich als Option beschrieben[10,23]. Klinische Studien hierzu liegen nicht vor.Bei der granulomatösen Rosazea finden sich disseminiert stehende bräunlich-rötliche Papeln und Knötchen, die bevorzugt an Oberlidern, Unterlidern, Jochbeinregion und perioral auftreten und bei Glasspateldruck ein lupoides Infiltrat aufweisen.…”

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“…Der Verlauf ist chronisch und oft sehr schwer behandelbar. Eine Therapie mit Isotretinoin (10-20 mg täglich) ist als Option beschrieben[23]. Aus eigener Erfahrung können wir berichten, dass einige Patienten mit therapierefraktärer granulomatöser Rosazea sehr gut auf eine orale Isotretinoin-Therapie ansprechen.Eine 48-jährige Patientin mit einer seit 10 Jahren schubweise exazerbierenden Rosazea stellte sich im akuten Schub vor und erhielt initial Metronidazol 2-mal 400 mg/Tag und Doxycyclin 2 -mal 100 mg/Tag über 14 Tage.…”

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Rosazea

Thielitz

Gollnick

2011

Hautarzt

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Systemic isotretinoin has been known for decades as an effective and safe therapeutic option in the treatment of severe and refractory forms of rosacea. It can also be used in special treatment-resistant forms of rosacea, e.g. granulomatous rosacea, as efficacious second-line therapy. Previously, the effect of isotretinoin in rosacea has been mainly studied in small cohorts or anecdotal reports. Recently, a big randomized double-blind dose-response and comparative study revealed that an optimized dosage of 0,3 mg/kg was superior to other dosages and non-inferior to doxycycline as gold standard of systemic rosacea treatment and proved effective and safe in papulopustular and phymatous subtypes. However, the substance is still not licensed for this indication The efficacy of isotretinoin in rosacea is probably mainly related to anti-inflammatory mechanisms as well as anti-oxidative, anti-angiogenic and antifibrotic properties. The classical antiseborrheic effect of isotretinoin might play a role in special subtypes like the phymatous type or rosacea fulminans.

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Akne und Rosazea

Cited by 7 publications

References 47 publications

Abuse of anabolic‐androgenic steroids and bodybuilding acne: an underestimated health problem

Abuse of anabolic‐androgenic steroids and bodybuilding acne: an underestimated health problem

Treatment of ocular rosacea with 40 mg doxycycline in a slow release form

Rosazea

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