Air leaks from the respiratory tract in mechanically ventilated children with severe respiratory disease

Isoflurane for Life-Threatening Bronchospasm: A 15-Year Single-Center Experience

“…Pneumothorax is another documented complication of mechanical ventilation, and this risk is increased substantially in the setting of bronchospasm and air trapping. 37–39 In this series, only one patient developed air leak while being treated with isoflurane. Improved gas exchange and decreased levels of ventilatory support secondary to isoflurane administration are potential explanations for the low incidence of pneumothoraces in these patients.…”

“…Pneumothorax is another documented complication of mechanical ventilation, and this risk is increased substantially in the setting of bronchospasm and air trapping 37–39 . In this series, only one patient developed air leak while being treated with isoflurane.…”

Respiratory syncytial virus and human metapneumovirus in severe lower respiratory tract infections in children under two

“…In our study, pneumothorax was significantly the most frequently encountered complication (13.6%) with RSV infection (p = 0.01). Strong positive correlation between the incidence of air leaks and high ventilatory pressure or large tidal volume was found by Briassoults et al [27]. Hui et al [26] reported a case of life-threatening bilateral pneumothorax in an infant with severe bronchiolitis, while Odek et al [28] and Pollack et al [29] each reported a case of spontaneous bilateral pneumothorax in an infant with RSV bronchiolitis.…”

Distinctive clinical features of spontaneous pneumoperitoneum in neonates: A retrospective analysis

“…Several possible origins of free air in cases of SP were presumed: Intrathoracic, gynecologic, intra-abdominal, iatrogenic, and miscellaneous[ 2 , 18 , 19 ]. Among those, there were some suggested clinical factors with including inadequate mechanical ventilation, a massive cardiopulmonary resuscitation, air leak syndrome, and other pulmonary conditions associated with prematurity[ 9 , 10 , 20 ]. Of these, pneumothorax is a frequent preceding sign and has been demonstrated to show a favorable clinical course in most of the reported cases[ 2 , 7 , 8 ].…”