2010
DOI: 10.1111/j.1468-3083.2010.03592.x
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Aggravating factors for melasma: a prospective study in 197 Tunisian patients

Abstract: This study identifies a number of factors associated with the severity of melasma. Further epidemiological studies in this type of population, in particular, to investigate triggering factors, are justified by the aesthetic damage caused by melasma in dark-skinned patients, lack of efficacy of existing treatments, non-compliance with photoprotection recommendations and the challenge of treatment.

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Cited by 90 publications
(136 citation statements)
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References 25 publications
(43 reference statements)
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“…This can be explained by UV radiation directly inducing the increase of melanogenic activity, thereby causing the development of epidermal pigmentation and occurs more intensely in regions with melasma than in the adjacent skin. 22,23 A 2013 study conducted in Brazil on the epidemiological characteristics of facial melasma identified the predominance of centro-facial melasma (51.7%), followed by mixed melasma (43.4%).…”
mentioning
confidence: 99%
“…This can be explained by UV radiation directly inducing the increase of melanogenic activity, thereby causing the development of epidermal pigmentation and occurs more intensely in regions with melasma than in the adjacent skin. 22,23 A 2013 study conducted in Brazil on the epidemiological characteristics of facial melasma identified the predominance of centro-facial melasma (51.7%), followed by mixed melasma (43.4%).…”
mentioning
confidence: 99%
“…Higher incidence of 51% was noted in a study conducted by Cheffai S, et al 14 and a lower incidence of 22.4% was reported in a study by Pathak M.A et al 15 In our study maximum number of patients were found to have Fitzpatrick skin type 4(60%) followed by Fitzpatrick skin types 3 and 5(23.3% and 16.6% respectively) which is consistent with study conducted by Zachian T F et al (68%). 3 In our study malar pattern was found to be the most common pattern observed in 58.3% followed by centrofacial in 40%.…”
Section: Discussionmentioning
confidence: 77%
“…8 The centrofacial pattern in 55% -75%, the malar pattern in 24% -43%, and the mandibular pattern in 1.5% -2% patients are three distinct clinical patterns. 10,11 Its exact etiology is poorly understood but often imputed to genetic predisposition, pregnancy and oral contraceptives, endocrinopathies, or drugs (hormones, anticonvulsants, phenothiazines, phototoxic agents) ingestion. 3,4 Pigmented cosmetic contact dermatitis is another recognized etiologic factor.…”
Section: Resultsmentioning
confidence: 99%