Age modifies the risk of atrial fibrillation among athletes: A systematic literature review and meta-analysis

Ayinde, Hakeem; Schweizer, Marin L.; Crabb, Victoria; Ayinde, Adedayo; Abugroun, Ashraf; Hopson, James R.

doi:10.1016/j.ijcha.2018.01.002

Cited by 23 publications

(24 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the contrary, the findings provided by a recent meta-analysis including six cohort studies and two case-control studies with a total of 9113 subjects showed a significantly increased risk of incident and prevalent AF among athletes compared to the general population (OR = 1.64; CI: 1.10-2.43). 37 In addition to LA dilatation, several other mechanisms, alone or in combination, could contribute to atrial fibrillation in competitive athletes. Vagal tone and bradycardia are more prevalent in athletes, and bradycardia has been associated with atrial fibrillation in individuals with normal cardiac structure and function.…”

Section: Discussionmentioning

confidence: 99%

Left atrial volume in elite athletes: A meta‐analysis of echocardiographic studies

Cuspidi

Sala

Tadić

et al. 2019

Scandinavian Med Sci Sports

View full text Add to dashboard Cite

Aim Information on left atrium (LA) enlargement, as assessed by LA volume (LAV) instead of LA diameter, in the athletic population is scanty. To expand current knowledge on this issue, we performed an updated meta‐analysis of echocardiographic studies. Design The Ovid MEDLINE, PubMed, and Cochrane CENTRAL databases were searched for English language articles without time restriction up to February 2018 through focused, high sensitive search strategies. Studies were identified by crossing the following search terms: “athletes,” “physical training,” “left atrial size,” “left atrial volume,” “atrial function,” and “echocardiography.”. Results Overall, 3145 subjects (2425 elite athletes and 720 active but not trained healthy controls) were included in 16 studies. Average LAV indexed to BSA (LAVI) was 37% higher in athletes as compared to nonathletic controls (31.0 ± 1.4 mL/m2 vs 22.2 ± 0.9 mL/m2), the standard means difference (SMD) being 1.12 ± 0.13 (CI: 0.86‐1.89, P < 0.0001). SMD was higher in high‐dynamic/high‐static trained athletes (1.78 ± 0.24, CI: 1.30‐2.20, P < 0.001) than in high‐dynamic/low‐static trained athletes 1.00 ± 0.16, CI: 0.70‐1.30, P < 0.001). The statistical difference did not change after correction for publication bias and was not affected by a single study effect. Conclusions Our meta‐analysis suggests that the adaptation of LA to intensive physical training in elite athletes is characterized by a marked increase in LAVI; LA dilation is more pronounced in the subgroup of high‐dynamic/high‐static trained athletes. The functional and clinical implications related to advanced LA dilation in athletes and particularly in those engaged in high‐dynamic/high‐static disciplines deserve further investigations.

show abstract

Section: Discussionmentioning

confidence: 99%

Left atrial volume in elite athletes: A meta‐analysis of echocardiographic studies

Cuspidi

Sala

Tadić

et al. 2019

Scandinavian Med Sci Sports

View full text Add to dashboard Cite

show abstract

“…The third meta-analysis published in 2018 identified six cohort studies and two case-control studies totaling 9113 individuals. Athletes were at increased risk of AF (odds ratio 1.64); however, when adjusted for age, this effect was only identified in those < 54 years of age [ 29 ]. Older athletes were not at increased risk of AF compared to age-matched sedentary controls.…”

Section: Methodsmentioning

confidence: 99%

Atrial Fibrillation (AF) in Endurance Athletes: a Complicated Affair

Stergiou

Duncan

2018

Curr Treat Options Cardio Med

View full text Add to dashboard Cite

Purpose of reviewA complex relationship exists between exercise and atrial fibrillation (AF). Moderate exercise reduces AF risk whereas intense strenuous exercise has been shown to increase AF burden. It remains unclear at which point exercise may become detrimental. Overall, endurance athletes remain at lower cardiovascular risk and experience fewer strokes. The questions that arise therefore are whether AF is an acceptable byproduct of strenuous exercise, whether athletes who experience AF should be told to reduce exercise volume and how should they be managed. This review aims to critically review the literature and advise on how best to manage athletes with AF.Recent findingsEmerging evidence suggests that female athletes may exhibit lower risk of AF, but data is limited in female endurance athletes.SummaryAF is more prevalent in endurance athletes, particularly men and those who competed at a young age. Data is lacking in females and ethnic minorities. Current evidence suggests that treatment options for AF in athletes are similar to those used in the general population; however, medical therapy may be poorly tolerated. Catheter ablation is effective and can allow return to full competition.

show abstract

“…20 Furthermore, several meta-analysis showed that the risk of AF is significantly higher in athletes compared with non-athletes. 25,26 Baseline obesity and weight gain are well-established independent risk factors for AF. 13,[27][28][29] Several studies have demonstrated that the association between obesity and AF risk can be modified by physical activity, suggesting that by improving fitness the adverse effect of obesity can be attenuated.…”

Section: Discussionmentioning

confidence: 99%

High fitness might be associated with the development of new‐onset atrial fibrillation in obese non‐athletic adults

et al. 2020

View full text Add to dashboard Cite

Atrial Fibrillation (AF) is the most common sustained arrhythmia with an increasing incidence and marked impact on morbidity and mortality. 1,2 Despite its rising prevalence, and its direct association with several risk factors, including cardiac and extracardiac diseases, the aetiology of AF remains partially unknown. 3,4 One of the modifiable risk factors for AF is obesity, an endemic problem that is also increasing in its prevalence in the last decades. 5,6 While the association of baseline obesity and incident AF among healthy adults is based on robust clinical data, there are some conflicting data, especially with respect to the obesity paradox. 7,8 Moreover, the association between obesity, cardiorespiratory fitness and incident AF is even more complex and poorly understood. On the one hand, low fitness levels are considered to be an independent risk factor for AF, 9 and physical activity and exercise are recommended by the Heart Rhythm Society for primary and secondary prevention for AF. 10 On the other hand, large observational studies

show abstract

Age modifies the risk of atrial fibrillation among athletes: A systematic literature review and meta-analysis

Cited by 23 publications

References 29 publications

Left atrial volume in elite athletes: A meta‐analysis of echocardiographic studies

Left atrial volume in elite athletes: A meta‐analysis of echocardiographic studies

Atrial Fibrillation (AF) in Endurance Athletes: a Complicated Affair

High fitness might be associated with the development of new‐onset atrial fibrillation in obese non‐athletic adults

Contact Info

Product

Resources

About