Age Differences in Clinical Characteristics, Health care, and Outcomes after Ischemic Stroke in China

Abstract

In CNSR, differences in stroke clinic characteristics and health care were observed among various age groups, and the old patients, receiving lower levels of stroke care, had the worst outcomes. Knowledge of the age differences in ischemic stroke may be helpful to appropriately allocate the limited health resources and to improve stroke outcomes.

Trends in In-Hospital Mortality among Patients with Stroke in China

“…Many of these factors were similar across stroke types, which included older age, male, northern and western regions and which had previously been associated with larger risk of short-term mortality after stroke, and underscored the need to implement strategies to bridge these socio-demographic gaps in stroke care [4], [14], [20]. In this study, patients whose primary payer was the basic health insurance had more odds of mortality in hospital.…”

“…It is now becoming the first leading cause of death in China [1]. Mortality of stroke at discharge significantly increased with age, with 1.15%, 1.46%, 3.31%, and 7.63% in-hospital mortality according to age group (≤45,46–65,66–79, ≥80 years old) respectively, and the very old patients had the worst outcomes even after adjusted by prognostic factors[4]. Now, demographic ageing is occurring at an unprecedented rate worldwide; the proportion of Chinese aged 65 and over will increase from 4% in 2000 to 14% by 2025, amounting to 200 million old people [5].…”

The Antiaging Activity and Cerebral Protection of Rapamycin at Micro‐doses

“…We next tested whether the neuron‐protective activities of micro‐dose rapamycin could be translated into disease prevention in animal models. Acute cerebral ischemic infarction (an aged‐related disease that causes neuron death and brain damage ) was employed. In a C57BL/6 mice model of acute ischemic cerebral infarction induced by transient MCAO, the animals were divided into six groups (n = 10 in each group) and pretreated by different dose of rapamycin (0.1, 1, 10, 100, 1000 μ g/kg/day, intraperitoneal (i.p.)…”

One‐year Clinical Prediction in Chinese Ischemic Stroke Patients Using the CHADS2 and CHA2DS2‐VASc Scores: The China National Stroke Registry

“…The NVAF prevalence is age dependent, which rises by 1% per year in patients under 60 and 15% per year in those over 85. The prevalence of other cerebrovascular risk factors also increases with age . In the NVAF patients without other risk factors and without the use of OAC, the stroke event rate in patients older than 75 years of age is twice that of the patients ages 65–74 .…”