Adverse reactions of fluorescein angiography: a prospective study

Lira, Rodrigo Pessoa Cavalcanti; Oliveira, Cleriston Lucena de Andrade; Marques, Marta Virgínia Ribeiro Brito; Silva, Alaine Rocha; Pessoa, Cristiano de Carvalho

doi:10.1590/s0004-27492007000400011

Cited by 66 publications

(54 citation statements)

References 20 publications

(36 reference statements)

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“…Nausea rates of 0.7% (3) , 2.9% (4) and 6.83% were found (1) . In another study the subgroup of diabetic patients experienced the highest nausea rate in more than 15% of the angiograms (5) , but hypertensive and elderly patients did not show increase in such reactions (6) .…”

Section: Discussionmentioning

confidence: 95%

“…In another study the subgroup of diabetic patients experienced the highest nausea rate in more than 15% of the angiograms (5) , but hypertensive and elderly patients did not show increase in such reactions (6) . Previous adverse reactions seems to be a powerful risk factor for future exams (1,2,4) . Some authors claim rates of complications as high as 48.6% when patient had experienced symptoms in a prior angiography (4) .…”

Section: Discussionmentioning

confidence: 99%

“…Adolf von Bayer synthesized fluorescein dye in 1871, and Novotny and Alvis developed a graphic system for sequential records of fluorescein flow through the ocular fundus in 1960 (1) . Fluorescein angiography is a diagnostic method used to assess chorioretinal disorders.…”

Section: Introductionmentioning

confidence: 99%

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Anafilaxia com convulsões após angiografia com fluoresceína em paciente ambulatorial

Balbino

Silva

2012

Einstein (São Paulo)

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Fluorescein is associated with minor adverse effects during retinal angiography, and most of these effects are not severe and not related to immunological mechanism. However, on rare occasions, anaphylatoid reaction can occur, and fatalities involving fluorescein have been described. Life threatening complications after intravenous injection of sodium fluorescein require immediate intervention. Trainings for professionals are needed to standardize treatment for this event.Keywords: Anaphylaxis; Seizures/chemically induced; Fluorescein angiography/adverse effects; Fluoresceins/administration & dosage; Retinal diseases; Injections, intravenous; Case reports RESUMO A fluoresceína endovenosa é associada a pequenos efeitos adversos durante a angiografia da retina, a maioria deles sem gravidade e não relacionada a mecanismos imunológicos. Entretanto, em raras ocasiões, pode ocorrer reação anafilactoide; fatalidades envolvendo o uso de fluoresceína têm sido descritas. Complicações graves após injeção endovenosa de fluoresceína requerem ação imediata da equipe envolvida, assim como treinamento regular para padronizar o tratamento.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

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Anafilaxia com convulsões após angiografia com fluoresceína em paciente ambulatorial

Balbino

Silva

2012

Einstein (São Paulo)

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“…The most commonly used angiography methods include fluorescein angiography (FA) [1] and indocyanine green angiography (ICGA) [2]. However, these angiography methods are invasive and require dye injection into the human body, which can occasionally have adverse effects [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Eye-motion-corrected optical coherence tomography angiography using Lissajous scanning

Chen

Hong

Makita

et al. 2018

Biomed. Opt. Express

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Abstract:To correct eye motion artifacts in en face optical coherence tomography angiography (OCT-A) images, a Lissajous scanning method with subsequent software-based motion correction is proposed. The standard Lissajous scanning pattern is modified to be compatible with OCT-A and a corresponding motion correction algorithm is designed. The effectiveness of our method was demonstrated by comparing en face OCT-A images with and without motion correction. The method was further validated by comparing motion-corrected images with scanning laser ophthalmoscopy images, and the repeatability of the method was evaluated using a checkerboard image. A motion-corrected en face OCT-A image from a blinking case is presented to demonstrate the ability of the method to deal with eye blinking. Results show that the method can produce accurate motion-free en face OCT-A images of the posterior segment of the eye in vivo. Y. Jia, "Automated motion correction using parallel-strip registration for wide-field en face OCT angiogram," Biomed.

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“…Current standard retinal imaging techniques, such as optical coherence tomography (OCT), color fundus photography or fluorescein angiography (FA) are widely used to provide information on healthy and diseased vascular structures [6]. However, these technologies fail to visualize the finest capillary network due to limited imaging resolution, or involve the invasive use of contrast agents, which may be associated with the risk of adverse reactions [7,8]. More importantly, the aforementioned techniques do not generally provide information about parafoveal capillary hemodynamics, which may be essential for best prediction of future development of vascular pathology over the chronic course of diabetes.…”

Section: Introductionmentioning

confidence: 99%

Computational fluid dynamics assisted characterization of parafoveal hemodynamics in normal and diabetic eyes using adaptive optics scanning laser ophthalmoscopy

Bernabéu¹,

Lammer²,

Cai³

et al. 2016

Biomed. Opt. Express

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Diabetic retinopathy (DR) is the leading cause of visual loss in working-age adults worldwide. Previous studies have found hemodynamic changes in the diabetic eyes, which precede clinically evident pathological alterations of the retinal microvasculature. There is a pressing need for new methods to allow greater understanding of these early hemodynamic changes that occur in DR. In this study, we propose a noninvasive method for the assessment of hemodynamics around the fovea (a region of the eye of paramount importance for vision). The proposed methodology combines adaptive optics scanning laser ophthalmoscopy and computational fluid dynamics modeling. We compare results obtained with this technique with in vivo measurements of blood flow based on blood cell aggregation tracking. Our results suggest that parafoveal hemodynamics, such as capillary velocity, wall shear stress, and capillary perfusion pressure can be noninvasively and reliably characterized with this method in both healthy and diabetic retinopathy patients.

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Adverse reactions of fluorescein angiography: a prospective study

Cited by 66 publications

References 20 publications

Anafilaxia com convulsões após angiografia com fluoresceína em paciente ambulatorial

Anafilaxia com convulsões após angiografia com fluoresceína em paciente ambulatorial

Eye-motion-corrected optical coherence tomography angiography using Lissajous scanning

Computational fluid dynamics assisted characterization of parafoveal hemodynamics in normal and diabetic eyes using adaptive optics scanning laser ophthalmoscopy

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