Adverse Mid-Term Outcome Following RVOT Reconstruction Using the Contegra Valved Bovine Jugular Vein

O conduto valvulado bovino contegra, um biomaterial para o tratamento cirúrgico de cardiopatias congênitas

“…Distal anastomosis stenosis with supravalvular conduit dilation was also found a cause for conduit explanation 14 . Corno et al 38 reported that postoperative intervention was due to twisted or stenotic conduit in 2 of 5 patients.…”

“…Histologic examination of the explanted conduits revealed excessive intimal peel formation forming an annular membrane at the level of the distal anastomosis with infiltrations of lymphocytes and macrophages 11,14,20,34 . Severe perigraft scarring reaction was also observed 14 .…”

“…Dilation of the right ventricular outflow patch and conduit may progress 14,20 . In an attempt to maintain conduit valve geometry and competency, a ring-supported Contegra can be an alternative.…”

“…Conduit plasty was necessary in 6 (0.4%), and reintervention to the conduit or to the pulmonary arteries in 83 (4.9%) patients. The conduit reimplantation was due to severe stenosis (excessive gradient) of the distal anastomosis refractory to interventional treatment 9,14,24,33,35 , (pseudo)aneurysm of the proximal anastomosis 19 , progressive right ventricular dysfunction caused by severe conduit regurgitation 18,20,33 , endocarditis 11,35 or graft degeneration 35 .…”

Outcomes of truncus arteriosus repair with bovine jugular vein conduit

“…[5] Contegra results vary in reports, although long-term complication is usually conduit stenosis which is mostly seen in smaller diameter conduits. [6,7] Dilatation of the Contegra conduit is rare. In this study, we aimed to analyze the outcomes of TA repair using the Contegra conduit for the RVOT reconstruction.…”