Advances in Magnetic Noble Metal/Iron-Based Oxide Hybrid Nanoparticles as Biomedical Devices

Abstract

The study of the noble metal magnetic hybrid nanoparticles is a really promising topic from both the scientific and the technological points of views, with applications in several fields. Iron oxide materials which are hybridized with noble metal nanoparticles (NPs) have attracted increasing interest among researchers because of their cooperative effects on combined magnetic, electronic, photonic, and catalytic activities. This review article contains a summary of magnetic noble metal/iron oxide nanoparticle systems potentially useful in practical biomedical applications. Among the applications, engineered devices for both medical diagnosis and treatments were considered. The preparation to produce different structures, as blends or core-shell structures, of several nanometric systems was also considered. Several characterization techniques available to describe the structure, morphology and different kinds of properties of hybrid nanoparticles are also included in this review.

Recent Advances in Magnetite Nanoparticle Functionalization for Nanomedicine

“…Through this method mostly result dumbbell-like, core-satellite, or sometimes star-shaped structures, but core-shell nanoparticles can only result after multiple repetitions of the coating procedure. The main disadvantage of this method is the low yield synthesis, as many gold nanoparticles result [131]. Moreover, the reduction of Au 3+ into Au 0 takes place at the boiling point of the watery solution (80-90 • C), which might lead to an oxidation of Fe 3 O 4 and loss of magnetic properties.…”

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“…HNPs are important due to their multi-functionalities, which are difficult to achieve by a simple mixture of individual components. Due to the combination of physical and chemical (magnetic and optical) properties of compound substances, they can be used in various fields, such as chemistry, physics, microelectronics, biotechnology, catalysis and medicine [1][2][3][4][5].…”

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“…[ 268 ] For example, in tumor imaging and contour selection, MRI provides high‐resolution soft tissue information while CT offers real‐time 3‐dimensional hard tissue information. [ 269 ] Various MNPs were used as multimodal contrast agents for MRI‐CT imaging modes. These offered a more precise diagnostic tool for the clinical settings.…”