Advances in bioconversion of glycerol to 1,3-propanediol: Prospects and challenges

Sun, Yaqin; Shen, Jianjian; Lü, Yan; Zhou, Junhu; Jiang, Lili; Chen, Yang; Yuan, Jinlong; Feng, Enmin; Xiu, Zhilong

doi:10.1016/j.procbio.2018.05.009

Cited by 103 publications

(51 citation statements)

References 172 publications

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“…Microbial production from glycerol seems to be sustainable even though some obstacles should be overcome to scale up the process to produce 1,3‐propanediol from glycerol (e. g. low productivity and high costs). The first steps toward industrialization have been taken in Jiangsu, China, where a facility with a capacity of 20,000 tons/a has been recently built …”

Section: Catalytic Production Of Platform Chemicals From Lignocellulomentioning

confidence: 99%

Recent Advances in the Catalytic Production of Platform Chemicals from Holocellulosic Biomass

et al. 2019

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This Review discusses novel catalytic pathways of lignocellulosic biomass to value‐added chemicals including biomass‐derived sugar alcohols, organic acids, furans and biohydrocarbons. These production approaches are undertaken by biological, chemical and thermochemical transformations or a combination of them. Nevertheless, the majority of research in this area is focused on the design of heterogeneous catalysts to convert value‐added products from holocellulosic biomass. Biorefineries represent the peak of biomass processes in order to produce valuable chemicals and liquid fuels avoiding the utilization of corroding and toxic elements. The aim of the present Review is to offer the readers a broad overview of recent holocellulosic‐based chemical and fuels production technologies via heterogeneous catalysis. There is also an overview of the economic aspects to efficiently produce these platform chemicals at industrial scale. To summarize this Review, an outlook and conclusions of the reported processes to date is provided.

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Section: Catalytic Production Of Platform Chemicals From Lignocellulomentioning

confidence: 99%

Recent Advances in the Catalytic Production of Platform Chemicals from Holocellulosic Biomass

et al. 2019

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“…DuPont has successfully achieved the commercialization of PDO through industrial biotechnology using glucose as the start material, which was an excellent for promoting the commercialization of PTT and its application . Another promising pathway for biological production of PDO refers to the microbial conversion of glycerol . Using glycerol as the raw material has a significant advantage that the feedstock is available as a by‐product of biodiesel production, producing a large amount at low cost.…”

Section: Nanocellulosementioning

confidence: 99%

“…185 Another promising pathway for biological production of PDO refers to the microbial conversion of glycerol. 186 Using glycerol as the raw material has a significant advantage that the feedstock is available as a by-product of biodiesel production, producing a large amount at low cost. In 2013, the first plant for PDO production from biodiesel by-product crude glycerol started construction in Jiangsu, China, with a capacity of 50 000 ton year −1 .…”

Section: Microcrystalline Cellulose (Mcc)mentioning

confidence: 99%

“…Formation of precursor compounds for bio-based materials production from hemicellulose-derived xylose (MA: maleic anhydride; LA: lactic acid; GVL: γ-valerolactone; 1,4-BDO: 1,4-butanediol; DALA: 5-aminolevulinic acid). 185,186,283,285 and lignin as solid phases and hemicellulose as hydrolyzate. Organosolv fractionation could provide an efficient pathway to achieve an integrated utilization of the biomass polymeric components.…”

Section: Conclusion and Prospectivementioning

confidence: 99%

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High value‐added monomer chemicals and functional bio‐based materials derived from polymeric components of lignocellulose by organosolv fractionation

Zhang

Cai

Qin

et al. 2019

Biofuels Bioprod Bioref

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Organosolv fractionation (OF) is a promising method for lignocellulosic biomass biorefining to produce biofuels, biochemicals, and biomaterials. The fractionated polymeric components may be good feedstocks to produce bio‐based materials such as green polymers via chemical or biological conversion. However, related work to specify the bio‐based materials production via organosolv fractionation of lignocellulosic biomass is relatively scarce. In this work we have provided a comprehensive review of typical organosolv fractionation for isolating cellulose, hemicelluloses, and lignin, as well as the high value‐added monomer chemicals and functional materials derived from the fractionated components and their potential applications developed in recent years, primarily including the modified cellulose fibers for polymer materials, cellulose nanocrystals (CNCs), polysaccharide‐derived platform precursors for synthesis of bio‐based polymers, lignin‐derived dispersants, surfactants, carbon materials, and hemicellulose‐derived functional materials, etc. This work suggests that organosolv fractionation of lignocellulosic biomass could be a good entry to biomass refinery for high value‐added and functional materials production. However, there are still many challenges that should be overcome in terms of the fundamental, technical, and economic aspects for the organosolv fractionation process, formation of precursor compounds, synthesis of the bio‐based materials, design of product properties and functions, and the integration of the entire process. © 2019 Society of Chemical Industry and John Wiley & Sons, Ltd

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“…K. pneumoniae is mostly used for PDO synthesis at large scale because of its natural ability to produce the B12 co-enzyme, a very important factor for microbial PDO synthesis [19]. The biotechnological production of PDO is extensively studied by multiple research groups because of the major development of market demands worldwide for PDO [20][21][22]. PDO plays an important role in the synthesis of biodegradable plastics, namely for the polytrimethyleneterephtalalte (PTT) production [18,23].…”

Section: Introductionmentioning

confidence: 99%

Klebsiella pneumoniae – a useful pathogenic strain for biotechnological purposes: 1,3-propanediol biosynthesis

Mitrea

Trif

RUSU³

et al. 2019

Preprint

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Background Despite being a well-known human pathogen, Klebsiella pneumoniae plays a significant role in the biotechnology field, being considered as a microbial cell factory in terms of valuable chemicals biosynthesis. In fermentation processes, K. pneumoniae is mostly used to biosynthesize 1,3-propanediol (PDO), a very important intermediate compound utilized in the biodegradable bioplastics industry. This strain owns the ability to metabolize glycerol and to produce PDO under both aerobic and anaerobic circumstances, and under low oscillations of pH. Results In this work, we investigated the K. pneumoniae strain DSMZ 2026 in batch bioreactor cultivation. The bacterial strain was inoculated in 2 L culture broth containing 43.5 g·L- 1 main substrate and the pH was adjusted at 7 at the beginning of the process. After 12 h of batch cultivation, the pH values decreased to 4.77, and we obtained 51 g·L-1 wet biomass, 17 g·L-1 PDO, while the starting substrate reached 15 g·L- 1. The morphology of K. pneumoniae cells was analyzed on both solid and liquid media, by being identified large mucoid colonies on Columbia agar, and individual and grouped cells were observed by methyl blue staining. Conclusion From this study it can be concluded that K. pneumoniae can grow successfully in mineral broth under anaerobic environment and low decrease of pH, and can biosynthesize valuable chemicals like PDO.

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Advances in bioconversion of glycerol to 1,3-propanediol: Prospects and challenges

Cited by 103 publications

References 172 publications

Recent Advances in the Catalytic Production of Platform Chemicals from Holocellulosic Biomass

Recent Advances in the Catalytic Production of Platform Chemicals from Holocellulosic Biomass

High value‐added monomer chemicals and functional bio‐based materials derived from polymeric components of lignocellulose by organosolv fractionation

Klebsiella pneumoniae – a useful pathogenic strain for biotechnological purposes: 1,3-propanediol biosynthesis

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