Advanced breast cancer: A randomized study of doxorubicin or mitoxantrone in combination with cyclophosphamide and vincristine

Abstract

Both VAC and VNC are effective regimens in advanced breast cancer. While the confidence limits in this study mean the response rate advantages of VAC could have arisen by chance, younger patients with adverse prognostic factors may warrant consideration of the VAC regimen.

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis

“…TNBC is an aggressive subtype of breast cancer, which tends to grow and spread more quickly than other subtypes [ 27 – 30 ]. Available endocrine and HER2-directed therapies are ineffective against TNBC.…”

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis

“…TNBC is an aggressive subtype of breast cancer, which tends to grow and spread more quickly than other subtypes [ 27 – 30 ]. Available endocrine and HER2-directed therapies are ineffective against TNBC.…”

Prophylactic use of lamivudine for hepatitis B exacerbation in post-operative breast cancer patients receiving anthracycline-based adjuvant chemotherapy

“…Considering that anthracyclines are some of the most widely used and effective drugs to treat patients with breast cancer in the adjuvant setting as well as patients with metastatic disease (Bennett et al , 1988; Henderson et al , 1989; Green et al , 1996; Fossati et al , 1998; Pai and Nahata, 2000; Crown et al , 2002), the number of reports is limited (Lai et al , 1998; Rossi et al , 2001; Lee et al , 2003). These results included a heterogeneous population in terms of the use of a prophylactic antiviral agent.…”

A Systematic Overview of Chemotherapy Effects in Breast Cancer

“…The toxicity was claimed to be lower or with a different pro le for Mito, but a slightly better antitumoural effect was noticed for Doxo (126,155,158,161,168,172). However, a trend in the opposite direction was noticed in a study of 217 randomised patients, although suboptimal doses of Doxo or Epi were used (147).…”

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis

“…TNBC is an aggressive subtype of breast cancer, which tends to grow and spread more quickly than other subtypes [ 27 – 30 ]. Available endocrine and HER2-directed therapies are ineffective against TNBC.…”

Prophylactic use of lamivudine for hepatitis B exacerbation in post-operative breast cancer patients receiving anthracycline-based adjuvant chemotherapy

“…Considering that anthracyclines are some of the most widely used and effective drugs to treat patients with breast cancer in the adjuvant setting as well as patients with metastatic disease (Bennett et al , 1988; Henderson et al , 1989; Green et al , 1996; Fossati et al , 1998; Pai and Nahata, 2000; Crown et al , 2002), the number of reports is limited (Lai et al , 1998; Rossi et al , 2001; Lee et al , 2003). These results included a heterogeneous population in terms of the use of a prophylactic antiviral agent.…”

A Systematic Overview of Chemotherapy Effects in Breast Cancer

“…The toxicity was claimed to be lower or with a different pro le for Mito, but a slightly better antitumoural effect was noticed for Doxo (126,155,158,161,168,172). However, a trend in the opposite direction was noticed in a study of 217 randomised patients, although suboptimal doses of Doxo or Epi were used (147).…”

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis

“…TNBC is an aggressive subtype of breast cancer, which tends to grow and spread more quickly than other subtypes [ 27 – 30 ]. Available endocrine and HER2-directed therapies are ineffective against TNBC.…”

Prophylactic use of lamivudine for hepatitis B exacerbation in post-operative breast cancer patients receiving anthracycline-based adjuvant chemotherapy

“…Considering that anthracyclines are some of the most widely used and effective drugs to treat patients with breast cancer in the adjuvant setting as well as patients with metastatic disease (Bennett et al , 1988; Henderson et al , 1989; Green et al , 1996; Fossati et al , 1998; Pai and Nahata, 2000; Crown et al , 2002), the number of reports is limited (Lai et al , 1998; Rossi et al , 2001; Lee et al , 2003). These results included a heterogeneous population in terms of the use of a prophylactic antiviral agent.…”

A Systematic Overview of Chemotherapy Effects in Breast Cancer

“…The toxicity was claimed to be lower or with a different pro le for Mito, but a slightly better antitumoural effect was noticed for Doxo (126,155,158,161,168,172). However, a trend in the opposite direction was noticed in a study of 217 randomised patients, although suboptimal doses of Doxo or Epi were used (147).…”