2016
DOI: 10.1097/wnr.0000000000000612 View full text |Buy / Rent full text
|
|

Abstract: Given evidence that mitogen-activated protein kinase (MAPK) activation is part of the nongenomic actions of thyroid hormones, we investigated the possible consequences of hyperthyroidism for the cognitive functioning of adult rats. Young adult rats were treated with L-thyroxine or saline. Twenty rats in each group were exposed to Morris water maze testing, measuring their performance in a hidden-platform spatial task. In a separate set of rats not exposed to Morris water maze testing (untrained rats), the expr… Show more

Help me understand this report

Search citation statements

Order By: Relevance
Select...
1
1
0
2
0

Year Published

2018
2018
2018
2018

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

0
2
0
Order By: Relevance
“…4b). Hyperthyroidism can affect many behavioral responses including anxiety, depression, hyperactivity, impaired learning, and spatial memory (Yu et al, 2015; Bitiktas et al, 2016; Rakov et al, 2016). However, hyperthyroidism has not been definitively associated with aggression.…”
Section: Discussionmentioning
See 1 more Smart Citation
Create an account to read the remaining citation statements from this report. You will also get access to:
  • Search over 1.2b+ citation statments to see what is being said about any topic in the research literature
  • Advanced Search to find publications that support or contrast your research
  • Citation reports and visualizations to easily see what publications are saying about each other
  • Browser extension to see Smart Citations wherever you read research
  • Dashboards to evaluate and keep track of groups of publications
  • Alerts to stay on top of citations as they happen
  • Automated reference checks to make sure you are citing reliable research in your manuscripts
  • 7 day free preview of our premium features.

Trusted by researchers and organizations around the world

Over 130,000 students researchers, and industry experts at use scite

See what students are saying

rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…4b). Hyperthyroidism can affect many behavioral responses including anxiety, depression, hyperactivity, impaired learning, and spatial memory (Yu et al, 2015; Bitiktas et al, 2016; Rakov et al, 2016). However, hyperthyroidism has not been definitively associated with aggression.…”
Section: Discussionmentioning
“…Therefore, alterations in thyroid hormone signaling are likely to affect behavior. Indeed, pharmacological induction of hyperthyroidism in rodents can cause an array of behavioral effects, including changes in locomotor activity, muscle strength, motor coordination, learning, memory, and affective behaviors (Yu et al, 2015; Bitiktas et al, 2016; Rakov et al, 2016). Behavioral effects differ based on the specific pharmacological or genetic induction of elevated thyroid function.…”
Section: Introductionmentioning