Adsorption of Poly(Acrylic Acid)-Graft-Poly(Ethylene Glycol) on Polyelectrolyte Multilayers

Klages, Claus‐Peter; Hartwig, Sven; Schmolke, Hannah

doi:10.1007/978-3-642-19038-4_17

Cited by 4 publications

(4 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PEMs consisting of PAH and PAA grow with small thickness increment and in the linear mode if both constituents are deposited at pH = 7 [5]. Therefore it is reasonable to assume that the first three PEMs in Table I are linearly growing while for the fourth representative, (PAH7.5/PAA3.5), the dissociation of PAA is suppressed at pH = 3.5, resulting in larger thickness increment of one double layer and, as shown in another paper [6], exponential growth. Pre-bond experiments shows that the ability to initialize the bond strongly decreases with increasing number of PEMs.…”

Section: Resultsmentioning

confidence: 94%

Temporary Wafer Bonding by Polyelectrolyte Interlayers

et al. 2014

Self Cite

View full text Add to dashboard Cite

Polyelectrolyte multilayers of just a few nanometers thickness were used for direct bonding of silicon, thermally oxidized silicon, and borosilicate wafers, respectively, and the bonded wafer pairs were characterized during and after annealing at temperatures up to 350 °C. Determination of surface energy as a measure of bond strength was performed in situ during annealing. The bond strengths show an interesting temperature dependence which can be utilized for temporary bonding of silicon wafers. Infrared transmission photographs as well as FTIR and XPS measurements suggest that the formation of hydrogen bubbles, generated by the reaction between water and silicon, contributes to the debonding at elevated temperatures.

show abstract

Section: Resultsmentioning

confidence: 94%

Temporary Wafer Bonding by Polyelectrolyte Interlayers

et al. 2014

Self Cite

View full text Add to dashboard Cite

show abstract

“…To quantify the adsorbed PAA‐ g ‐PEG amount in terms of the area density of monomeric EG units of PEG or, equivalently, the PEG layer thickness for an assumed packing density of PEG chains, a method based on FTIR‐ATR measurements, combined with spectra simulation is currently developed and will be described later in detail 48. In short, from IR measurements and spectra simulations of polycrystalline PEG bulk material with randomly orientated PEG helices the Drude–Lorentz parameters are extracted for a selection of vibrational bands in the region of wavenumbers between 800 and 1500 cm −1 .…”

Section: Resultsmentioning

confidence: 99%

Poly(acrylic acid)‐graft‐poly(ethylene glycol) preparation and adsorption on polyelectrolyte multilayers (PEMs) for custom‐made antiadhesive surfaces

Schmolke

Hartwig

Klages

2011

Physica Status Solidi (a)

Self Cite

View full text Add to dashboard Cite

531 2155 900 Web: www.tu-braunschweig. de/iot In this study, we report on a simple and versatile method for PEGylation of surfaces which is applicable practically independent of the substrate material: a poly(acrylic acid)graft-poly(ethylene glycol) (PAA-g-PEG) copolymer was synthesized with grafting ratios g in the range of g ¼ 20-2 [acrylic acid (AA) monomers to PEG side chains] and adsorbed either on bare stainless steel or on stainless steel precoated with different types of polyelectrolyte multilayers (PEMs) from aqueous solution. For PAA-g-PEG synthesis two principal routes were compared with respect to yield and control of g: the active ester route using different carbodiimide coupling agents and the route via poly(acrylic acid chloride) (PAA-Cl).Measurements based on Fourier transform infrared spectroscopy in attenuated total reflection mode (FTIR-ATR) showed that the adsorbed amount of PAA-g-PEG copolymer is in general drastically enhanced, compared to bare stainless steel as a substrate, when a suitable PEM is used as an interlayer. The amount was also found to be strongly dependent on the type of PEM and to increase with increasing thickness of the PEM interlayer. The stability of highly PEGylated PEMs and the influence of thermal crosslinking on stability were investigated by immersing the PEM-PEG samples for 1 week into 1 M NaCl solution at pH 4.5 and 0.15 M phosphate buffered saline (PBS) at pH 7.4, respectively.

show abstract

“…2͑b͒ gives an indication of the amount of PAA-g-PEG adsorbed as well as a hint toward a pronounced vertical PEG chain orientation on the surface. 34 Interestingly, the amount of adsorbed PAA-g-PEG copolymer depends on the type of PEM used as a base layer. In general, PAH/PAA-PEMs assembled under acid conditions ͑e.g., at PAH/PAA solution pHs of 2.0/2.0͒ show low binding affinity for PAA͑200͒-5-PEG͑5͒, whereas a high PEGylation degree, i.e., a high amount of adsorbed PAA͑200͒-5-PEG͑5͒, can be achieved for PAH/PAA-PEMs deposited at pH of 7.5/3.5 as well as for PDADMAC/PAA-PEMs.…”

Section: G Parallel Plate Flow Chamber Experimentsmentioning

confidence: 99%

Polyelectrolyte multilayer surface functionalization of poly(dimethylsiloxane) (PDMS) for reduction of yeast cell adhesion in microfluidic devices

et al. 2010

Self Cite

View full text Add to dashboard Cite

Polyelectrolyte multilayers (PEMs) based on the combinations poly(diallyldimethylammonium chloride)∕poly(acrylic acid) (PDADMAC∕PAA) and poly(allylamine hydrochloride)∕PAA (PAH∕PAA) were adsorbed on poly(dimethylsiloxane) (PDMS) and tested for nonspecific surface attachment of hydrophobic yeast cells using a parallel plate flow chamber. A custom-made graft copolymer containing poly(ethylene glycol) (PEG) side chains (PAA-g-PEG) was additionally adsorbed on the PEMs as a terminal layer. A suitable PEM modification effectively decreased the adhesion strength of Saccharomyces cerevisiae DSM 2155 to the channel walls. However, a further decrease in initial cell attachment and adhesion strength was observed after adsorption of PAA-g-PEG copolymer onto PEMs from aqueous solution. The results demonstrate that a facile layer-by-layer surface functionalization from aqueous solutions can be successfully applied to reduce cell adhesion strength of S. cerevisiae by at least two orders of magnitude compared to bare PDMS. Therefore, this method is potentially suitable to promote planktonic growth inside capped PDMS-based microfluidic devices if the PEM deposition is completed by a dynamic flow-through process.

show abstract

Adsorption of Poly(Acrylic Acid)-Graft-Poly(Ethylene Glycol) on Polyelectrolyte Multilayers

Cited by 4 publications

References 23 publications

Temporary Wafer Bonding by Polyelectrolyte Interlayers

Temporary Wafer Bonding by Polyelectrolyte Interlayers

Poly(acrylic acid)‐graft‐poly(ethylene glycol) preparation and adsorption on polyelectrolyte multilayers (PEMs) for custom‐made antiadhesive surfaces

Polyelectrolyte multilayer surface functionalization of poly(dimethylsiloxane) (PDMS) for reduction of yeast cell adhesion in microfluidic devices

Contact Info

Product

Resources

About