Adrenochrome Pigmentation

Autonomic drugs in the treatment of canine and feline glaucoma – Part I: Medications that lower intraocular pressure by increasing the outflow of aqueous humour

“…Epinephrine can undergo oxidation to adrenochrome, a melanin pigment. Adrenochrome material is often found in the lower conjunctival sac (Cashwell et al 1977), but it can also be deposited in the corneal epithelium (Kaiser et al 1992) and nasolacrimal ducts (Spaeth 1967). Basically, these deposits do not cause any disorders although a case has been described of persistent superotemporal corneal erosion as a result of an adrenochrome deposit on the upper tarsus (Pardos et al 1980).…”

Autonomic drugs in the treatment of canine and feline glaucoma – Part I: Medications that lower intraocular pressure by increasing the outflow of aqueous humour

“…Epinephrine can undergo oxidation to adrenochrome, a melanin pigment. Adrenochrome material is often found in the lower conjunctival sac (Cashwell et al 1977), but it can also be deposited in the corneal epithelium (Kaiser et al 1992) and nasolacrimal ducts (Spaeth 1967). Basically, these deposits do not cause any disorders although a case has been described of persistent superotemporal corneal erosion as a result of an adrenochrome deposit on the upper tarsus (Pardos et al 1980).…”

Autonomic drugs in the treatment of canine and feline glaucoma – Part I: Medications that lower intraocular pressure by increasing the outflow of aqueous humour

“…Epinephrine can undergo oxidation to adrenochrome, a melanin pigment. Adrenochrome material is often found in the lower conjunctival sac (Cashwell et al 1977), but it can also be deposited in the corneal epithelium (Kaiser et al 1992) and nasolacrimal ducts (Spaeth 1967). Basically, these deposits do not cause any disorders although a case has been described of persistent superotemporal corneal erosion as a result of an adrenochrome deposit on the upper tarsus (Pardos et al 1980).…”

Autonomic drugs in the treatment of canine and feline glaucoma – Part I: Medications that lower intraocular pressure by increasing the outflow of aqueous humour

“…Epinephrine can undergo oxidation to adrenochrome, a melanin pigment. Adrenochrome material is often found in the lower conjunctival sac (Cashwell et al 1977), but it can also be deposited in the corneal epithelium (Kaiser et al 1992) and nasolacrimal ducts (Spaeth 1967). Basically, these deposits do not cause any disorders although a case has been described of persistent superotemporal corneal erosion as a result of an adrenochrome deposit on the upper tarsus (Pardos et al 1980).…”