2021
DOI: 10.1007/s12022-021-09685-y
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Adrenal Rests in the Uro-genital Tract of an Adult Population

Abstract: Ectopic adrenal rests are a rare condition which can be found in various sites, generally in the retroperitoneum or pelvis along the path of gonadal descent. Their real prevalence is unknown. Males are more commonly affected, at least in the pediatric age. Adrenal rests are usually clinically silent and incidentally found in surgical samples, mostly in the pediatric population, and rarely in adults. With the aim of increasing knowledge and estimating the prevalence of ectopic adrenocortical tissue in the adult… Show more

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Cited by 8 publications
(9 citation statements)
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“…In surgical pathology, most adrenal rests are discovered as incidental microscopic findings in various surgical specimens including kidneys or gonads (particularly, spermatic cord [22], rete testis [23][24][25], epididymis [26], ovary/paraovarian [22,[27][28][29][30][31][32][33], salpinx and parasalpinx [22,34,35] ). A recent surgical series from adults identified ectopic adrenal rests in both males and females with a more frequent Fig.…”
Section: Question 2: Why Do Pathologists Need To Know Ectopic or Hete...mentioning
confidence: 99%
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“…In surgical pathology, most adrenal rests are discovered as incidental microscopic findings in various surgical specimens including kidneys or gonads (particularly, spermatic cord [22], rete testis [23][24][25], epididymis [26], ovary/paraovarian [22,[27][28][29][30][31][32][33], salpinx and parasalpinx [22,34,35] ). A recent surgical series from adults identified ectopic adrenal rests in both males and females with a more frequent Fig.…”
Section: Question 2: Why Do Pathologists Need To Know Ectopic or Hete...mentioning
confidence: 99%
“…2 Sporadic nodular adrenocortical disease. This photomicrograph illustrates a sporadic nodular adrenocortical disease The green circle outlines the lesion presentation in para-ovarian tissues [22]. Rare locations of adrenal rests include the placenta [36], broad ligament [22,37,38], retroperitoneum [39,40], urinary bladder and prostate [41], groin [42,43], choroid plexus [44], spine [45][46][47], and lung [48,49].…”
Section: Question 2: Why Do Pathologists Need To Know Ectopic or Hete...mentioning
confidence: 99%
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“…37,78 They are helpful also in defining ACC of ectopic adrenal tissue and in metastases. 79 In particular, SF-1 emerged as the most reliable, with a diagnostic sensitivity and specificity of 98% and 100%, respectively. 33,53,[80][81][82][83][84][85][86][87] In addition, ACC can variably express mesothelial (calretinin and D2-40) and neuronal (synaptophysin and neurofilaments) markers and is negative for epithelial membrane antigen, carcinoembryonic antigen, and chromogranin A.…”
Section: Pathology Of Pediatric Adrenal Cortical Tumors and Related S...mentioning
confidence: 97%