Abstract:OBJECTIVE: To evaluate safety and therapeutic effect along 12 months of allogenic adipose tissue-derived stromal/stem cells (ASCs) transplantation+cholecalciferol(VITD) in patients with recent-onset type 1 diabetes (T1D).METHODS: Prospective, phase II, open trial, pilot study in which patients with recent onset T1D received ASCs(1Kgx106 cells) and VITD 2000UI/day for 12 months(group 1) and were compared to controls with standard insulin therapy (group 2). Adverse events, C-peptide area under the curve(CPAUC), … Show more
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