Nature volume 444, issue 7121, P847-853 2006 DOI: 10.1038/nature05483
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Evan D. Rosen, Bruce M. Spiegelman
Abstract:

Adipocytes have been studied with increasing intensity as a result of the emergence of obesity as a serious public health problem and the realization that adipose tissue serves as an integrator of various physiological pathways. In particular, their role in calorie storage makes adipocytes well suited to the regulation of energy balance. Adipose tissue also serves as a crucial integrator of glucose homeostasis. Knowledge of adipocyte biology is therefore crucial for understanding the pathophysiological bas…

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