Adhesion and Viability of Two Enterococcal Strains on Covalently Grafted Chitosan and Chitosan/κ-Carrageenan Multilayers

Bratskaya, Svetlana; Marinin, Dmitry; Simon, Frank; Synytska, Alla; Zschoche, Stefan; Busscher, Henk J.; Jager, Debbie De; Mei, van der Henny C.

doi:10.1021/bm700620j

Cited by 87 publications

(71 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…CHI/k-carrageenan films were found to have a greater effect in decreasing initial bacterial adhesion than a thinner CHI coating, which was explained by the greater hydration of the multilayer films. [203] Adhesion of negatively charged enterococci was slightly enhanced on CHI-terminated multilayers, but the anti-bacterial effect was absent on k-carregan-terminated multilayers. Heparin with its anti-thrombogenicity and strong hydrophilicity also prevented adhesion of bacteria.…”

Section: Antibacterial Propertiesmentioning

confidence: 99%

Multiple Functionalities of Polyelectrolyte Multilayer Films: New Biomedical Applications

Boudou¹,

Crouzier²,

Ren³

et al. 2010

Advanced Materials

686

702

View full text Add to dashboard Cite

The design of advanced functional materials with nanometer- and micrometer-scale control over their properties is of considerable interest for both fundamental and applied studies because of the many potential applications for these materials in the fields of biomedical materials, tissue engineering, and regenerative medicine. The layer-by-layer deposition technique introduced in the early 1990s by Decher, Moehwald, and Lvov is a versatile technique, which has attracted an increasing number of researchers in recent years due to its wide range of advantages for biomedical applications: ease of preparation under "mild" conditions compatible with physiological media, capability of incorporating bioactive molecules, extra-cellular matrix components and biopolymers in the films, tunable mechanical properties, and spatio-temporal control over film organization. The last few years have seen a significant increase in reports exploring the possibilities offered by diffusing molecules into films to control their internal structures or design "reservoirs," as well as control their mechanical properties. Such properties, associated with the chemical properties of films, are particularly important for designing biomedical devices that contain bioactive molecules. In this review, we highlight recent work on designing and controlling film properties at the nanometer and micrometer scales with a view to developing new biomaterial coatings, tissue engineered constructs that could mimic in vivo cellular microenvironments, and stem cell "niches."

show abstract

Section: Antibacterial Propertiesmentioning

confidence: 99%

Multiple Functionalities of Polyelectrolyte Multilayer Films: New Biomedical Applications

Boudou¹,

Crouzier²,

Ren³

et al. 2010

Advanced Materials

686

702

View full text Add to dashboard Cite

show abstract

“…Previous studies done using this technique were the use of chitosan/hyaluronan and chitosan/κ-carrageenan multilayers [11]. In this study, polyethylenimine (Figure 1) was used instead of chitosan then layered with the three types of carrageenan (Figure 1).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Polyethylenimine/Carrageenan Multilayer against Pathogenic Bacteria

Briones¹,

Sato²,

Bigol³

2014

ACES

View full text Add to dashboard Cite

The multilayer of polyethylenimine (PEI) and carrageenan (κ, ι, λ) formed by layer-by-layer assembly was investigated for its antibacterial activity against Enterobacter cloaceae, Staphylococcus aureus and Enterococcus faecalis 29505 for potential use as coating on biomaterial surface. All the multilayers exhibited growth inhibition. PEI/Iota carrageenan multilayer was effective in inhibiting the growth of the E. cloaceae, S. aureus and E. faecalis while PEI/Lambda carrageenan was effective in inhibiting the growth of E. cloaceae. Results of the paper strip test for combined action of carrageenan and PEI showed synergism with regards to bacterial growth inhibition. The multilayers had also contact-killing effect with the test organisms. The multilayer was also characterized by atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS) and biomolecular interaction analysis.

show abstract

“…In order to overcome these disadvantages, another study combined chitosan with carrageenan multilayers, to provide additional anti-adhesion properties [94].…”

Section: Chitosanmentioning

confidence: 99%

Biofunctionalization of surfaces using polyelectrolyte multilayers

Hartmann¹,

Krastev²

2018

Nano Online

View full text Add to dashboard Cite

Biomaterials play a central role in modern strategies in regenerative medicine and tissue engineering to restore the structure and function of damaged or dysfunctional tissue and to direct cellular behavior. Both biologically derived and synthetic materials have been extensively explored in this context. However, most materials when implanted into living tissue initiate a host response. Modern implant design therefore aims to improve implant integration while avoiding chronic inflammation and foreign body reactions, and thus loss of the intended implant function. Directing these processes requires an in-depth understanding of the immunological processes that take place at the interface between biomaterials and the host tissue. The physicochemical properties of biomaterial surfaces (charge, charge density, hydrophilicity, functional molecular domains, etc.) are decisive, as are their stiffness, roughness and topography. This review outlines specific strategies, using polyelectrolyte multilayers to modulate the interactions between biomaterial surfaces and biological systems. The described coatings have the potential to control the adhesion of proteins, bacteria and mammalian cells. They can be used to decrease the risk of bacterial infections occurring after implantation and to achieve better contact between biological tissue and implants. In summary, these results are important for further development and modification of surfaces from different medical implants.

show abstract

Adhesion and Viability of Two Enterococcal Strains on Covalently Grafted Chitosan and Chitosan/κ-Carrageenan Multilayers

Cited by 87 publications

References 50 publications

Multiple Functionalities of Polyelectrolyte Multilayer Films: New Biomedical Applications

Multiple Functionalities of Polyelectrolyte Multilayer Films: New Biomedical Applications

Antibacterial Activity of Polyethylenimine/Carrageenan Multilayer against Pathogenic Bacteria

Biofunctionalization of surfaces using polyelectrolyte multilayers

Contact Info

Product

Resources

About