Adherence to Antiretroviral Therapy and Associated Factors Among Human Immunodeficiency Virus Positive Patients Accessing Treatment at Health Centers in East Gojjam Zone, Northwest Ethiopia, 2019: Community Based Cross Sectional Study

Tariku, Mengistie Kassahun; Worede, Daniel Tarekegn; Belete, Abebe Muche

doi:10.2139/ssrn.4296462

Cited by 1 publication

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“…Patients may experience side efects such as nausea, dizziness, or fatigue, which can make it difcult for them to attend their health facility appointments regularly. In addition, the high pill burden associated with these regimens may lead to nonadherence and missed appointments [14,29]. HIV-positive patients who were taking ART drugs for ≥12 months had fourfold higher odds of keeping on-time appointments than those patients who were taking ART drugs for less than 12 months.…”

Section: Discussionmentioning

confidence: 99%

“…HIV-positive patients who were taking ART drugs for ≥12 months had fourfold higher odds of keeping on-time appointments than those patients who were taking ART drugs for less than 12 months. Patients who have taken ARTdrugs for <12 months may have adverse drug events, existing coinfections and/or comorbidities, severely low hemoglobin, a low body mass index (severe malnutrition), and/or very low CD4 counts [14,29], which may cause them to miss the scheduled appointment.…”

Section: Discussionmentioning

confidence: 99%

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On-Time Appointment Keeping and Associated Factors among Human Immunodeficiency Virus-Positive Adult Patients Accessing Antiretroviral Therapy at Health Centers in East Gojjam Zone, Northwest Ethiopia, 2019

Tariku,

Belete,

Worede

et al. 2023

AIDS Research and Treatment

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Background. The magnitude of on-time appointment keeping among HIV-positive adult patients was not identified in Ethiopia. Hence, this study aimed to assess on-time appointment keeping and associated factors among human immunodeficiency virus-positive patients accessing antiretroviral therapy in the East Gojjam Zone, Northwest Ethiopia. Methods. A community-based cross-sectional study was performed on 830 HIV-positive patients from April 1 to May 10, 2019, in East Gojjam Zone. A systematic random sampling technique was used to include study subjects, and data were collected through face-to-face interviews. Bivariable and multivariable binary logistic regression analyses were performed. Independent variables with a P value of <0.05 were considered statistically significant cut points. Results. The prevalence of on-time appointment keeping was 62.1%. Being >24 years old (adjusted odds ratio (AOR) = 2.13; 95% confidence interval (CI) = 1.54–4.25), being unmarried (AOR = 0.59; 95% CI = 0.45–0.82), taking a drug regimen of tenofovir + lamivudine (3TC) + efavirenz (EFV) (AOR = 2.11; 95% CI = 1.84–3.62), taking ART ≥12 months (AOR = 4.32; 95% CI = 2.22–8.40), having a mobile (AOR = 2.22; 95% CI = 1.44–3.64), and getting adherence support (AOR = 1.83; 95% CI = 1.16; 95% 1.16–3.50) were significant factors. Conclusion. On-time appointment keeping was low. Adherence support and appointment reminders should be strengthened.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%