Adenosquamous carcinoma of the skin. An aggressive mucin- and gland-forming squamous carcinoma

Primary cutaneous adenosquamous carcinoma: a case report and review of the literature

“…This is diagnostic of adenocarcinoma. Classically, actinic keratosis 2–4 has been described in the epidermis of these patients, but we have found neither solar elastosis nor keratinocytic dysplasia in our case. Inmunohistochemical stains reveal cytokeratin positivity in both components.…”

Sclerosing Squamous Cell Carcinoma of the Skin, An Underemphasized Locally Aggressive Variant: A 20-Year Experience

“…We (unpublished series) and others have noted the presence of desmoplastic stroma in association with ACS 15,16 . Desmoplastic SCC and ACS show a similar pattern, consisting of infiltrating nests of carcinoma set in a sclerotic stroma, with the common presence of perineural invasion.…”

Adenosquamous Carcinoma of the Skin: A Case Report

“…Lesion thickness, microscopic perineural invasion, and immunosuppression are important predictors of extensive local disease and recurrence [4]. Taking into account the previously investigated cases in the literature, our case is similar with respect to male sex, white race, and history of actinic damage [1,2]. However, the patient was neither old nor immunosuppressed.…”