Adenoid cystic carcinoma of the head and neck: evaluation with MR imaging and clinical-pathologic correlation in 27 patients.

Sigal, R.; Monnet, O.; Baere, T. de; Micheau, C; Shapeero, Lorraine G.; Juliéron, M.; Bosq, Jacques; Vanel, D.; Piekarski, J.D.; Luboinski, B.

doi:10.1148/radiology.184.1.1319079

Cited by 133 publications

(55 citation statements)

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“…Among low-grade MECs, tumours usually had a hyperintense area on T 2 weighted images, reflecting a cystic architectural pattern because of the existence of abundant mucin-secreting cells. A similar tendency of increased signal intensity on T 2 weighted images in lowergrade malignancies was reported for adenoid cystic carcinomas of the head and neck region [10]. In contrast with the previous literature that describes ill-defined margins on MR images as a predictor of high-grade malignancies [6][7][8][9], half of our low-grade MECs had illdefined margins on MR images, reflecting peritumoural inflammatory changes.…”

Section: Resultssupporting

confidence: 82%

MRI findings of mucoepidermois carcinoma of the parotid gland: correlation with pathological features

Kashiwagi

Dote²,

Kawano³

et al. 2012

BJR

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Objective: The aim of this study was to correlate the MRI appearance and pathological findings in each grade of the mucoepidermoid carcinoma (MEC) of the parotid gland. Methods: We reviewed surgically proven MECs of parotid glands in 20 patients. Pathologically, 5 tumours were high-grade, 3 were intermediate and 12 were lowgrade. MR images were evaluated with emphasis on signal intensities on T 2 weighted images, margin characteristics and lymph node metastasis, correlating these with pathological features. Results: Among the high-grade MECs, four out of five tumours showed inhomogeneous low to intermediate signal intensity on T 2 weighted images, reflecting high cellularity. All tumours had an ill-defined margin, reflecting invasive tumour growth. Among the intermediate-grade MECs, all three tumours showed intermediate signal intensity on T 2 weighted images and two tumours had an ill-defined margin. Among the low-grade MECs, 11 of the 12 tumours had a hyperintense area on T 2 weighted images because of the existence of abundant mucin secreting cells. Seven tumours had an ill-defined margin, reflecting peritumoural inflammatory changes rather than invasive tumour growth. Lymph node metastasis was seen in three highgrade MECs. Conclusion: MECs of the parotid gland show variable MRI findings reflecting their histological nature, which seems to have certain tendencies depending on the tumour grade.

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Section: Resultssupporting

confidence: 82%

MRI findings of mucoepidermois carcinoma of the parotid gland: correlation with pathological features

Kashiwagi

Dote²,

Kawano³

et al. 2012

BJR

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“…In our patients the tumor extension was often underestimated during the preoperative staging by means of imaging techniques as compared with the intraoperative and histopathological findings, while Sigal et al 23 reported an overestimation of the tumor size (Fig. 1).…”

Section: Discussionmentioning

confidence: 47%

Adenoid Cystic Carcinoma of the Skull Base

Issing¹,

Hemmanouil²,

Stöver³

et al. 1999

Skull Base

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“…Perineural infiltration was noted on MR images in nine of 27 patients with ACC in a previous study [15]. Additionally, 11 of 80 cases of perineural tumor extension reported by Ballantyne [1] and 11 ot" 52 cases reported by Parker [5] were of adenoid cystic origin.…”

Section: 21 Adenoid Cystic Carcinomamentioning

confidence: 83%

“…Repeat recurrences and distant metastases occur over many years finally killing the patient. Repeat surgical excision and RT are the treatment of choice [15].…”

Section: 21 Adenoid Cystic Carcinomamentioning

confidence: 99%

Perineural tumor extension along the trigeminal nerve: magnetic resonance imaging findings

Majoie

Hulsmans

Verbeeten

et al. 1997

European Journal of Radiology

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General rightsIt is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulationsIf you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. AbstractObjectice: To evaluate the magnetic resonance imaging (MRI) findings of 15 patients with perineural tumor extension along the trigeminal nerve in correlation with clinical data. ,~Iethods: The clinical records and MRI studies of 15 patients with perineura.l tumor extension along the trigeminal nerve were retrospectively reviewed. Imaging studies included plain and contrast-enhanced thin section Tl-weighted spin echo (T1-WSE) MRI with and without fat-suppression. The studies were compared to determine which sequence provided greatest tumor conspicuity and best depiction of tumor extent. The conspicuity of these tumors was assessed on the available sequences by two observers by consensus. Results: The contrast-enhanced Tl-weighted spin echo fat-suppressed images (TI-WSECEFS) demonstrated greatest tumor conspicuity and best depiction of tumor extent in the extracranial head and neck and skull base region. The conventional Tl-weighted spin echo pre-and postcontrast images were, however, diagnostic of perineural tumor extension in 11 patients due to the presence of considerable tumor bulk and extension well above the skull base. In the other four patients the perineural tumor was poorly visualized on the conventional TI-WSE images and well visualized on the fat-suppressed images. The mandibular division of the trigeminal nerve (V3) was most commonly involved (n = 10), followed by the maxillary. (V2; n = 5) and ophthalmic (VI; n = 2) division. Two patients had both mandibular as well as maxillary nerve involvement. The finding of perineural tumor extension had significant impact on patient management: based on the MR imaging study, the primary tumor was considered inoperable (n = 13), the extent of surgery was expanded (n = 2) and radiation therapy (RT) ports were extended (n = 12). Conclusion: Complete trigeminal nerve imaging is recommended when evaluating (suspected) head and neck malignancies with a high risk for perineural extension. In these cases thin section axial and coronal precontrast T1-WSE MR images and postcontrast TI-WSE MR images with fat-suppression should be obtained. In the rare event that artifacts degrade the quality of the fat-suppressed images, contrast-enhanced TI-WSE sequences without fat...

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Adenoid cystic carcinoma of the head and neck: evaluation with MR imaging and clinical-pathologic correlation in 27 patients.

Cited by 133 publications

References 0 publications

MRI findings of mucoepidermois carcinoma of the parotid gland: correlation with pathological features

MRI findings of mucoepidermois carcinoma of the parotid gland: correlation with pathological features

Adenoid Cystic Carcinoma of the Skull Base

Perineural tumor extension along the trigeminal nerve: magnetic resonance imaging findings

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