2011
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Abstract: Several studies have shown the protective and/or deleterious effects of dietary enrichment of single fatty acids (FAs) in several animal and cell-culture models of Alzheimer's disease (AD). However, potential interactions among dietary fatty acids are traditionally ignored. None of these studies has examined and compared the differential effects of FAs in combination, as well as alone, for their effects on amyloid β production or AD. Here we investigated the effects of omega-9 (oleic acid) and omega-6 (linolei… Show more

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“…The other major fatty acids were palmitic acid (C 16:1 , 15.89% of total fatty acids), palmitoleic acid (C 18:2 , 10.43% of total fatty acids), linoleic acid (C 18:0 , 4.69% of total fatty acids) and stearic acid (C 14:0 , 1.81% of total fatty acids), comprising more than 95% of total fatty acids in P. brevitarsis larvae. Oleic acid was also reported to be the primary fatty acid in the larvae of Imbrasia belina , Oryctes rhinoceros and Rhynchophorus phoenicis (21,22) are well known for decreasing risk of cancer, heart attack, atherosclerosis and dementia (23,24). …”
Section: Resultsmentioning
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“…The other major fatty acids were palmitic acid (C 16:1 , 15.89% of total fatty acids), palmitoleic acid (C 18:2 , 10.43% of total fatty acids), linoleic acid (C 18:0 , 4.69% of total fatty acids) and stearic acid (C 14:0 , 1.81% of total fatty acids), comprising more than 95% of total fatty acids in P. brevitarsis larvae. Oleic acid was also reported to be the primary fatty acid in the larvae of Imbrasia belina , Oryctes rhinoceros and Rhynchophorus phoenicis (21,22) are well known for decreasing risk of cancer, heart attack, atherosclerosis and dementia (23,24). …”
Section: Resultsmentioning
“…Aβ is a 40–42 amino acid peptide fragment derived by proteolysis from the integral membrane protein known as Aβ precursor protein (14). Aβ, the central constituent of senile plaques in AD, is known to exert toxic effects on neurons (15).…”
Section: Discussionmentioning
“…Not all antibodies work well with PFA-perfused sections. Different post-fixations either with acetone Brought to you by | University of Queensland -UQ Library Authenticated Download Date | 6/13/15 9:02 PM (at -20°C for 3-5 min), Triton X-100 (different concentrations), citrate buffer or microwaving (Amtul et al, 2010(Amtul et al, , 2011a(Amtul et al, ,b, 2012(Amtul et al, , 2013 can enhance the antigen signal in some circumstances. 3.…”
Section: Antibody Selection and Fixativementioning