Addition of drug/s to a chemotherapy regimen for metastatic breast cancer

Abstract

Trusted evidence. Informed decisions. Better health. Cochrane Database of Systematic Reviews REFERENCES References to studies included in this review Ahmann 1976a {published data only} * Ahmann DL, O'Connell MJ, Bisel HF. An evaluation of Cytoxan/ Adriamycin (CA) vs. Cytoxan/Adriamycin/5-Fluorouracil (CAF) vs. Cytoxan/5-Fluorouracil/Prednisone (CFP) in advanced breast cancer.

Survival and prognostic factors in oligometastatic breast cancer

“…These findings support the hypothesis that early maximal systemic therapy in OMBC is important. A ‘curative’ regimen, comparable to the regimens used in early breast cancer (doublet or triplet chemotherapy), provides the best chances of favorable response and may therefore be preferable [ 33 ]. The fact that the majority of patients in our cohort relapsed at new disease sites further supports the idea that optimal systemic therapy is key in achieving long-term remission.…”

Survival and prognostic factors in oligometastatic breast cancer

“…These findings support the hypothesis that early maximal systemic therapy in OMBC is important. A ‘curative’ regimen, comparable to the regimens used in early breast cancer (doublet or triplet chemotherapy), provides the best chances of favorable response and may therefore be preferable [ 33 ]. The fact that the majority of patients in our cohort relapsed at new disease sites further supports the idea that optimal systemic therapy is key in achieving long-term remission.…”

Selective anticancer effects and protection from chemotherapy by the botanical compound LCS101: Implications for cancer treatment

“…Many tumors are aggressive and resistant to conventional treatments, which themselves can impair the body's immunity and increase susceptibility to infection. The use of additional chemotherapy agents to established regimens can further increase tumor response, though this positive effect is offset by increased toxicity (8).…”

Mild hepatic macrovesicular steatosis may be a risk factor for hyperbilirubinaemia in living liver donors following right hepatectomy

“…The combination of antiretrovirals of different acting mechanisms, known as cocktail therapy, has proven highly effective in suppressing HIV replication and widely used to control the progression of AIDS 1. Inspired by the success of AIDS treatment, scientists have investigated anticancer drug combinations for the treatment of various types of cancer 2. Due to the heterogeneity of a tumor, cancer cells exist at different stages in the cell cycle.…”

Survival and prognostic factors in oligometastatic breast cancer

“…These findings support the hypothesis that early maximal systemic therapy in OMBC is important. A ‘curative’ regimen, comparable to the regimens used in early breast cancer (doublet or triplet chemotherapy), provides the best chances of favorable response and may therefore be preferable [ 33 ]. The fact that the majority of patients in our cohort relapsed at new disease sites further supports the idea that optimal systemic therapy is key in achieving long-term remission.…”

Selective anticancer effects and protection from chemotherapy by the botanical compound LCS101: Implications for cancer treatment

“…Many tumors are aggressive and resistant to conventional treatments, which themselves can impair the body's immunity and increase susceptibility to infection. The use of additional chemotherapy agents to established regimens can further increase tumor response, though this positive effect is offset by increased toxicity (8).…”

Mild hepatic macrovesicular steatosis may be a risk factor for hyperbilirubinaemia in living liver donors following right hepatectomy

“…The combination of antiretrovirals of different acting mechanisms, known as cocktail therapy, has proven highly effective in suppressing HIV replication and widely used to control the progression of AIDS 1. Inspired by the success of AIDS treatment, scientists have investigated anticancer drug combinations for the treatment of various types of cancer 2. Due to the heterogeneity of a tumor, cancer cells exist at different stages in the cell cycle.…”

Survival and prognostic factors in oligometastatic breast cancer

“…These findings support the hypothesis that early maximal systemic therapy in OMBC is important. A ‘curative’ regimen, comparable to the regimens used in early breast cancer (doublet or triplet chemotherapy), provides the best chances of favorable response and may therefore be preferable [ 33 ]. The fact that the majority of patients in our cohort relapsed at new disease sites further supports the idea that optimal systemic therapy is key in achieving long-term remission.…”

Selective anticancer effects and protection from chemotherapy by the botanical compound LCS101: Implications for cancer treatment

“…Many tumors are aggressive and resistant to conventional treatments, which themselves can impair the body's immunity and increase susceptibility to infection. The use of additional chemotherapy agents to established regimens can further increase tumor response, though this positive effect is offset by increased toxicity (8).…”

Mild hepatic macrovesicular steatosis may be a risk factor for hyperbilirubinaemia in living liver donors following right hepatectomy

“…The combination of antiretrovirals of different acting mechanisms, known as cocktail therapy, has proven highly effective in suppressing HIV replication and widely used to control the progression of AIDS 1. Inspired by the success of AIDS treatment, scientists have investigated anticancer drug combinations for the treatment of various types of cancer 2. Due to the heterogeneity of a tumor, cancer cells exist at different stages in the cell cycle.…”