Add-on Memantine Treatment for a Complicated Case of Juvenile Bipolar Mood Disorder with Co-morbid Obsessive-compulsive Disorder

Abstract

Journal of PsychiatryNo guidelines are currently available to dictate the most appropriate course of action in these cases. Memantine, a drug that is approved for Alzheimer's Disease (AD) with putative antiglutamate activity has been reported in successful management of some refractory cases of OCD as well as BMD. Here, we report a pharmacologicallychallenging case of an adolescent with comorbid BMD and OCD masquerading as school refusal behaviour (SRB) , that ultimately improved with add-on memantine to her treatment combo with great tolerability.This could open new treatment venues for such complicated cases.