Adaptive remodeling of the rabbit temporomandibular joint following discectomy and dietary variations

Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis

“…The fact that the small-size diet experimental group showed a lower level of decreasing condyle cartilage thickness, lower degraded cartilage areas, lower expression of ADAMTS-5 and less loss of the cartilage matrix and subchondral bone resorption, agrees with this assumption. It has been reported that although the soft diet plays a negative role in condyle development 5,9,10 , rabbits or rats that received TMJ discectomy had less degenerative cartilage changes 43,44 and higher condylar cartilage sulfate uptake 45 when fed with soft diet. Besides catabolic changes, the chondrocytes in mechanically induced degraded articular cartilage displayed the reparative capability, including the activities of phagocytizing dead cells 46 and proliferation 26,33,36,37 .…”

Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis

“…The fact that the small-size diet experimental group showed a lower level of decreasing condyle cartilage thickness, lower degraded cartilage areas, lower expression of ADAMTS-5 and less loss of the cartilage matrix and subchondral bone resorption, agrees with this assumption. It has been reported that although the soft diet plays a negative role in condyle development 5,9,10 , rabbits or rats that received TMJ discectomy had less degenerative cartilage changes 43,44 and higher condylar cartilage sulfate uptake 45 when fed with soft diet. Besides catabolic changes, the chondrocytes in mechanically induced degraded articular cartilage displayed the reparative capability, including the activities of phagocytizing dead cells 46 and proliferation 26,33,36,37 .…”

Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandible

“…There has been a considerable amount of research conducted to improve our understanding of growth and adaptation of the TMJ in response to experimental manipulations and clinical treatments. [18][19][20][21][22][23][24] The healthy TMJ is responsive to changes in its biomechanical and biophysical environment. Exposed to such changes, the TMJ may undergo substantial remodeling, an adaptive capacity not shared by many other joints.…”

Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis

“…The fact that the small-size diet experimental group showed a lower level of decreasing condyle cartilage thickness, lower degraded cartilage areas, lower expression of ADAMTS-5 and less loss of the cartilage matrix and subchondral bone resorption, agrees with this assumption. It has been reported that although the soft diet plays a negative role in condyle development 5,9,10 , rabbits or rats that received TMJ discectomy had less degenerative cartilage changes 43,44 and higher condylar cartilage sulfate uptake 45 when fed with soft diet. Besides catabolic changes, the chondrocytes in mechanically induced degraded articular cartilage displayed the reparative capability, including the activities of phagocytizing dead cells 46 and proliferation 26,33,36,37 .…”

Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandible

“…There has been a considerable amount of research conducted to improve our understanding of growth and adaptation of the TMJ in response to experimental manipulations and clinical treatments. [18][19][20][21][22][23][24] The healthy TMJ is responsive to changes in its biomechanical and biophysical environment. Exposed to such changes, the TMJ may undergo substantial remodeling, an adaptive capacity not shared by many other joints.…”

Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis

“…The fact that the small-size diet experimental group showed a lower level of decreasing condyle cartilage thickness, lower degraded cartilage areas, lower expression of ADAMTS-5 and less loss of the cartilage matrix and subchondral bone resorption, agrees with this assumption. It has been reported that although the soft diet plays a negative role in condyle development 5,9,10 , rabbits or rats that received TMJ discectomy had less degenerative cartilage changes 43,44 and higher condylar cartilage sulfate uptake 45 when fed with soft diet. Besides catabolic changes, the chondrocytes in mechanically induced degraded articular cartilage displayed the reparative capability, including the activities of phagocytizing dead cells 46 and proliferation 26,33,36,37 .…”

Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandible

“…There has been a considerable amount of research conducted to improve our understanding of growth and adaptation of the TMJ in response to experimental manipulations and clinical treatments. [18][19][20][21][22][23][24] The healthy TMJ is responsive to changes in its biomechanical and biophysical environment. Exposed to such changes, the TMJ may undergo substantial remodeling, an adaptive capacity not shared by many other joints.…”