2002
DOI: 10.1007/bf03032286
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Abstract: Open-heart surgery impaired both T cell proliferation and the antigen-presentation. Such synergistic impairment severely impaired adaptive immunity. This impairment was both severer and longer than we anticipated based on previous studies using the response of T cells to lectin as a marker of cell-mediated immunity.

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Cited by 4 publications
(1 citation statement)
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“…1 An open heart surgery, which is associated with the usage of CPB, has been reported to cause an in vitro temporary cellular immune depression, which is most pronounced in the first 2 days after surgery, may last for about 2 weeks, and is manifested by an in vitro attenuated lymphocytes response to mitogens, as well as change in T cell subpopulations. [4][5][6][7][8][9] Sano et al, 4 examined lymphocyte proliferation in vitro, after incubation with PPD antigen, in adults undergoing open heart surgery. They found that in the first 2 days after surgery the amount of lymphocytes proliferation was only 3.2% of the presurgical response.…”
Section: Discussionmentioning
confidence: 99%
“…1 An open heart surgery, which is associated with the usage of CPB, has been reported to cause an in vitro temporary cellular immune depression, which is most pronounced in the first 2 days after surgery, may last for about 2 weeks, and is manifested by an in vitro attenuated lymphocytes response to mitogens, as well as change in T cell subpopulations. [4][5][6][7][8][9] Sano et al, 4 examined lymphocyte proliferation in vitro, after incubation with PPD antigen, in adults undergoing open heart surgery. They found that in the first 2 days after surgery the amount of lymphocytes proliferation was only 3.2% of the presurgical response.…”
Section: Discussionmentioning
confidence: 99%