2010
DOI: 10.1590/s0102-695x2010000300017
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Abstract: RESUMO: "Toxicidade aguda do extrato aquoso de Psilocybe cubensis em camundongos". O Psilocybe cubensis (Ear.) Sing., Strophariaceae, é um cogumelo alucinógeno usado pelos humanos desde a antiguidade, causando diversos efeitos psicóticos. Ele contém dois derivados triptamínicos: psilocibina e psilocina, agonistas do receptor 5-HT2 (serotonina). O objetivo deste trabalho foi investigar os efeitos da administração do extrato aquoso do P. cubensis (EAPC) na toxicidade aguda de camundongos. Camundongos Swiss adult… Show more

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Cited by 5 publications
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“…There were no marked behavioral changes observed except for the group of animals exposed to PS. These behavioral responses have also been exhibited by those administered with P. cubensis (Kirsten and Bernardi, 2010 ), suggesting that these symptoms may be characteristic of hallucinogenic species of the Psilocybe genus. Taking into account the hematological parameters, the increased levels of LYM and WBC may serve as putative markers of an inflammatory response and also helps in predicting toxicity or pathological status.…”
Section: Discussionmentioning
confidence: 74%
“…There were no marked behavioral changes observed except for the group of animals exposed to PS. These behavioral responses have also been exhibited by those administered with P. cubensis (Kirsten and Bernardi, 2010 ), suggesting that these symptoms may be characteristic of hallucinogenic species of the Psilocybe genus. Taking into account the hematological parameters, the increased levels of LYM and WBC may serve as putative markers of an inflammatory response and also helps in predicting toxicity or pathological status.…”
Section: Discussionmentioning
confidence: 74%