Acute Psychosis as Clinical Manifestation of Tuberculous Meningitis

Pushkar, Durgesh; Patel, Madhabhai M.; Sachan, Rekha; R, Misra

doi:10.9734/bjmmr/2017/31747

Cited by 2 publications

(2 citation statements)

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“…[9,10] TBM per se has been observed to present as psychosis. [11,12] Pyrazinamide and rifampicin have linked to ATT-induced hepatic encephalopathy. [13] Furthermore, steroid is known to precipitate or induce psychosis in TBM.…”

Section: Discussionmentioning

confidence: 99%

Psychosis in Tuberculous Meningitis: A Case Series

Kumar,

Nigam,

Chakraborty

et al. 2024

PIJR

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Section: Discussionmentioning

confidence: 99%

Psychosis in Tuberculous Meningitis: A Case Series

Kumar,

Nigam,

Chakraborty

et al. 2024

PIJR

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“…This presentation was found in only 2 patients (5%) where spinal cord MRI had a primary role in the etiologic diagnosis by showing characteristic aspects of the tubercular origin. Two patients (5%) initially presented with psychiatric manifestations who had been diagnosed with NMT, this finding is rarely reported in the literature [ 8 ]. Seizures are seen in 18.5% of cases in NMT, regardless of HIV status [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

Neuromeningeal tuberculosis in HIV-negative patients: a retrospective study in Rabat, Morocco

Ahizoune¹,

Satte²,

Ajamat³

et al. 2022

Pan Afr Med J

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Neuro-Meningeal Tuberculosis (NMT) is a severe infection of the central nervous system which causes a public health problem in Morocco and in several countries in the world. In order to describe the epidemiological, clinical, paraclinical and outcome among NMT patients without HIV, we carried out a retrospective study at the neurology department of the Military Hospital of Rabat in Morocco, over a period of 17 years (2000-2017). Forty patients were included with a mean age of 44 years (± 18) and a sex ratio of 1.66. A history evoking the possibility of tuberculous origin was found in 8 patients (20%). Febrile confusion was the most common clinical manifestation and was observed in 22 patients (55%) followed by febrile meningeal syndrome in 12 patients (30%). The main abnormalities noted in brain magnetic resonance imaging (MRI) were: hydrocephalus in 13 cases (32.5%), intra-cranial tuberculomas in 10 patients (25%) and leptomeningitis in 9 cases (22.5%). Cerebrospinal fluid study found clear aspect in 29 patients (75%), direct acid fast bacilli smear examination was positive in 4 patients (10%) and positive culture in 4 patients (10%). The Polymerase chain reaction (PCR) study returned positive in 6 patients (35%) of the 17 patients tested. The outcome was good in 18 patients (45%) while 19 patients suffered from neurological sequelae (47.5%) and 3 cases of death recorded (7.5%). Febrile confusion was the most reported manifestation in our patients. Subacute onset of symptoms was the most predominant feature in our patients as reported in the literature. Our results are consistent with the literature and confirm the severity of this infectious disease, even in HIV-negative patients.

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Acute Psychosis as Clinical Manifestation of Tuberculous Meningitis

Cited by 2 publications

References 0 publications

Psychosis in Tuberculous Meningitis: A Case Series

Psychosis in Tuberculous Meningitis: A Case Series

Neuromeningeal tuberculosis in HIV-negative patients: a retrospective study in Rabat, Morocco

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