Acute Myeloid Leukemia Stem Cells—Updates and Controversies

Chung, Stephen S.; Park, Christopher Y.

doi:10.1002/9781118356203.ch11

Cited by 5 publications

(2 citation statements)

References 87 publications

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“…13,14 Despite the biological, molecular and clinical heterogeneity of leukemia, the occurrence of alterations is clear since the beginning of the hematopoietic differentiation program. However, while for acute and chronic myeloid leukemia a population of leukemic stem cells is responsible for their development and recurrence, 15,16 for lymphoblastic leukemias, their undifferentiated nature appears not to be phenotypic and may be related to the tumor microenvironment, 17,18 which contributes to the disease pathogenesis.…”

Section: Introductionmentioning

confidence: 99%

Report of the First National Consensus Meeting for Acute Leukemias Immunophenotyping

Arriaga-Pizano¹,

Ramírez-Ramírez²,

Prieto-Chávez³

et al. 2023

GMM

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Recommendations for the typing of hematological malignancies in Latin America were published in 2005. Carrying out a national meeting to update them was deemed necessary. Ninety-five professional experts on the subject were invited in order to analyze and contrast alternatives and reach a consensus. Consensus opinions were reached regarding indications, sample types and processing, antibodies, nomenclature and reporting of results for the diagnosis and monitoring of acute leukemias. This paper describes the recommendations and emphasizes on the need for national laboratories to adhere to them.

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Section: Introductionmentioning

confidence: 99%

Report of the First National Consensus Meeting for Acute Leukemias Immunophenotyping

Arriaga-Pizano¹,

Ramírez-Ramírez²,

Prieto-Chávez³

et al. 2023

GMM

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show abstract

“…13,14 A pesar de la heterogeneidad biológica, molecular y clínica de las leucemias, es clara la manifestación de alteraciones desde los inicios del programa de diferenciación hematopoyética. Sin embargo, mientras que para las leucemias mieloides agudas y crónicas una población de células troncales leucémicas es responsable de su desarrollo y recurrencia, 15,16 para las leucemias linfoblásticas su troncalidad aparentemente no es fenotípica y puede estar relacionada con el microambiente tumoral, 17,18 que contribuye a la patogénesis de la enfermedad.…”

Section: Introductionunclassified

Reporte de la Primera Reunión Nacional de Consenso para la Inmunofenotipificación de Leucemias Agudas

Arriaga-Pizano

Ramírez-Ramírez

Prieto-Chávez

et al. 2018

GMM

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En 2005 se publicaron recomendaciones para la tipificación de hemopatías malignas en Latinoamérica. Se consideró necesario realizar una reunión nacional para actualizarlas. Se convocaron y reunieron 95 profesionales expertos en el tema para analizar y contrastar alternativas y llegar a un consenso. Se alcanzaron opiniones de consenso en lo relativo a indicaciones, tipos y manejo de muestras, anticuerpos, nomenclatura e informe de resultados para el diagnóstico y seguimiento de las leucemias agudas. Las recomendaciones se describen en este artículo y se hace hincapié en la necesidad de que los laboratorios nacionales se apeguen a ellas.

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The Historical Relationship Between Meis1 and Leukemia

Meric

Kocabaş

2022

Advances in Experimental Medicine and Biology

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Acute Myeloid Leukemia Stem Cells—Updates and Controversies

Cited by 5 publications

References 87 publications

Report of the First National Consensus Meeting for Acute Leukemias Immunophenotyping

Report of the First National Consensus Meeting for Acute Leukemias Immunophenotyping

Reporte de la Primera Reunión Nacional de Consenso para la Inmunofenotipificación de Leucemias Agudas

The Historical Relationship Between Meis1 and Leukemia

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