2012
DOI: 10.1186/1477-9560-10-21
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Abstract: Hump-nosed pit viper (Genus Hypnale) is a medically important venomous snake in Sri Lanka and Southwestern India which causes significant morbidity and mortality. Envenoming of this snake results in hemostastic dysfunction, thrombotic microangiopathy, acute kidney injury and death. This case describes an authenticated first case of ischemic stroke in a 65 year old male following envenoming by H.hypnale in Sri Lanka.

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Cited by 26 publications
(19 citation statements)
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“…Cerebral infarction caused by snaclecs likely facilitates vipers to immobilize and capture their prey by inducing motor disability in animals, as illustrated in Figures 1 and 2. Despite a low occurrence, available data indicate that viper envenomation, including T. stejnegeri [34], leads to acute cerebral infarction in humans [4,[35][36][37][38][39]; however, experiments performed so far have not clarified the components responsible for viper envenomation-induced cerebral infarction in the venom. We suggest that Snaclecs may be the key component for viper envenomation-induced cerebral infarction.…”
Section: Discussionmentioning
confidence: 99%
“…Cerebral infarction caused by snaclecs likely facilitates vipers to immobilize and capture their prey by inducing motor disability in animals, as illustrated in Figures 1 and 2. Despite a low occurrence, available data indicate that viper envenomation, including T. stejnegeri [34], leads to acute cerebral infarction in humans [4,[35][36][37][38][39]; however, experiments performed so far have not clarified the components responsible for viper envenomation-induced cerebral infarction in the venom. We suggest that Snaclecs may be the key component for viper envenomation-induced cerebral infarction.…”
Section: Discussionmentioning
confidence: 99%
“…Ischemic stroke following Russell’s, saw-scaled, and hump-nosed viper bites have been previously reported. 10 , 19 21 It is believed to occur due to the procoagulant properties of snake venom and its direct action on vascular endothelial cells. 19 Paresthesia around the bite site reported in one patient is likely to represent direct effects of snake venom on peripheral nerves as has been previously observed.…”
Section: Discussionmentioning
confidence: 99%
“…Les principales espèces de vipères identifiées en Tunisie sont la vipère lebetine ( Macroviperalebetina ) (du nord au sud), la vipère à corne ( Cerastescerastes ) (région désertique)( Figure 5 ), la vipère d'Avicenne ( Cerastesvipera ) (Gafsa et Tozeur) et la vipère des pyramides ( Echiscarinatuspyramidium ) (Médenine) [ 1 ]. Le venin de vipères est une salive qui est un mélange complexe d′enzymes protéiques et de toxines en quantités variables [ 2 ]. Sur le plan clinique, il existe des signes locaux avec une inflammation (constante), la trace de morsure (inconstante), des signes hémorragiques, une nécrose et un syndrome des loges.…”
Section: Discussionunclassified