volume 29, issue 12, P812-818 2014
DOI: 10.1590/s0102-86502014001900008
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Abstract: . Design and supervised all phases of the study, critical revision. ABSTRACT PURPOSE:To investigate the effects of acute hyperglycemia on dexmedetomidine-induced preconditioning against renal ischemiareperfusion injury. METHODS:Sprague-Dawley rats were randomly arranged to the normoglycemic (NG) or hyperglycemic group (HG), with each group further divided into sham (no I/R injury), I/R (ischemia-reperfusion) and dex (given by dexmedetomidine) groups. Acute hyperglycemia was induced by intraperitoneal injectio…

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