Acute generalized livedo reticularis with myasthenialike syndrome revealing parvovirus B19 primary infection

Livedo reticularis: An update

“…81 A pattern of generalized LR and myasthenia-like syndrome has been described in association with parvovirus B19 infection. 83 Cutaneous findings resolved within 3 days of presentation with rest and antipyretic therapy. 83 The LR was believed to be caused by direct viral alteration of vascular smoothmuscle cells resulting in vasodilatation.…”

“…83 Cutaneous findings resolved within 3 days of presentation with rest and antipyretic therapy. 83 The LR was believed to be caused by direct viral alteration of vascular smoothmuscle cells resulting in vasodilatation. 83 …”

“…83 The LR was believed to be caused by direct viral alteration of vascular smoothmuscle cells resulting in vasodilatation. 83 …”

Detection of human parvovirus B19 DNA in 22% of 1815 cutaneous biopsies of a wide variety of dermatological conditions suggests viral persistence after primary infection and casts doubts on its pathogenic significance

“…These range from uncommon entities with a strong aetiological association to B19V, such as papular–purpuric ‘gloves‐and‐socks’ syndrome (PPGSS) to classical dermatological diseases with only a remote relation to the virus. These include Henoch–Schönlein purpura, erythema nodosum, erythema multiforme, palmar desquamation/keratolysis exfoliativa, dermatomyositis‐like rash, acute livedo reticularis, chronic urticaria, systemic sclerosis, chronic and acute pityriasis lichenoides, psoriasis, Behçet disease, granuloma annulare, necrotizing vasculitis, Wells syndrome, Melkersson–Rosenthal syndrome, hydroa vacciniforme, acute exanthematous pustulosis, Sweet syndrome and others . This association has been mostly based on serological proof of recent infection (i.e.…”

Parvovirus B19 infection associated with acute hepatitis and a purpuric exanthem

“…S ir , Human parvovirus (HPV) B19 infection shows a wide spectrum of cutaneous manifestations and, especially in adults, systemic involvement 1 –5 . Acute hepatitis and hepatic disorders are rare 6 …”