Acute febrile neutrophilic dermatosis (Sweet syndrome)

Greer, K. E.

doi:10.1001/archderm.111.11.1461

Cited by 25 publications

(2 citation statements)

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“…The resemblance of so-called atypical or bullous pyoderma gangraenosum to Sweet's syndrome [17][18][19][20] was noted in the discussion by Pegum [21J after presentation of a patient labeled as having 'bullous pyoderma gangraenosum' and chronic myeloid leukemia. These neutrophilic dermatoses are pail of the same spectrum, often without fever or neu trophilia, hence the unifying name AND -as the histologic pattern in these patients consistently displays an extensive diffuse dermal infiltrate of neutrophils often with leukocytoclasia 11,3], There have been over 60 patients reported with AND and myeloproliferative disease [6, 13-16, 22, 23]; the latter was usually detected months after the onset of the skin changes, although in some patients they were detected simultaneously [2,22]; a few patients with AND have been first observed after the malignant diagnosis was established.…”

Section: Discussionmentioning

confidence: 99%

Sweet’s Syndrome with Myelofibrosis and Leukemia: Partial Response to Interferon

Brodkin

Schwartz

1995

Dermatology

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Sweet’s syndrome with malignancy or acute neutrophilic dermatosis (AND) is an unusual cutaneous disorder seen most commonly in association with acute myelogenous leukemia. A large majority of patients with AND and malignancy have neoplasms of hematopoietic, plasma cell or lymphoid nature. The patient reported here had myelofibrosis, chronic myelogenous leukemia and Sweet’s syndrome. The individual lesions responded to intralesional interferon-α₂, which has not to our knowledge been reported previously. This result, however, was not as great as the response of AND to intralesional steroid injections.

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Section: Discussionmentioning

confidence: 99%

Sweet’s Syndrome with Myelofibrosis and Leukemia: Partial Response to Interferon

Brodkin

Schwartz

1995

Dermatology

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“…This syndrome was first described by Sweet [ 11 ] in 1964 and later on by other au thors [4,5,9], In 1979, Sweet [12] himself re- viewed the literature. It is a rare syndrome characterized by a severe febrile illness, ery thematous eruption, leukocytosis neutro philia and, histologically, by a dense dermal polymorphonuclear infiltrate.…”

Section: Commentmentioning

confidence: 99%