Infectious Disease Clinics of North America volume 18, issue 4, P861-882 2004 DOI: 10.1016/j.idc.2004.07.006 View full text
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Sanjay Sethi, Timothy F. Murphy

Abstract: Exacerbations are a characteristic feature of chronic obstructive pulmonary disease and contribute significantly to associated morbidity and mortality. Renewed interest in this common clinical problem and research using new investigative tools has enhanced substantially the understanding of the pathogenesis of exacerbations. Results of recent clinical trials and observational studies have allowed refinements in treatment of exacerbations that should im-prove patient outcomes. This article discusses a rational,…

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