1994
DOI: 10.1001/archderm.130.12.1530
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Acute erythroderma as an exclusion criterion for idiopathic CD4+ T lymphocytopenia

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Cited by 6 publications
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“…It has recently been recommended that acute erythroderma be an exclusion criteria for this immunodeficiency, because of a report of three patients who developed transient CD4+ T lymphocytopenia that resolved after their erythroderma resolved. It was proposed that the skin was sequestering the CD4+ lymphocytes during the erythroderma 16 …”
Section: Discussionmentioning
confidence: 99%
“…It has recently been recommended that acute erythroderma be an exclusion criteria for this immunodeficiency, because of a report of three patients who developed transient CD4+ T lymphocytopenia that resolved after their erythroderma resolved. It was proposed that the skin was sequestering the CD4+ lymphocytes during the erythroderma 16 …”
Section: Discussionmentioning
confidence: 99%
“…Increased IgE may be observed in erythroderma when caused by atopic dermatitis and drug reactions, although it has also been reported in other settings 4 . In a report by Griffiths et al ., 82 a decreased CD4 + T‐cell count was observed in patients with erythroderma in the absence of HIV disease, as a consequence of sequestration of the lymphocytes in the skin 82 . Circulating Sezary cells at greater than 20% are indicative of Sezary syndrome, but at less than 10% are a nonspecific finding in erythroderma 10,11 .…”
Section: Investigations/diagnosismentioning
confidence: 98%
“…4 T-helper lymphocytes are the most prominent cells in the skin infiltrate in erythroderma. 3,5,6 We have shown that the dermal infiltrate in patients with Sézary syndrome mainly express interleukin (IL)-4 (Th2 cytokine profile) in contrast to interferon (IFN)-g (Th1 cytokine profile) in benign reactive erythroderma. 7 Adhesion molecules are glycoproteins which mediate contact between cells with the extracellular matrix or between cells themselves.…”
mentioning
confidence: 99%