1998
DOI: 10.1055/s-2007-1010208 View full text |Buy / Rent full text
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Abstract: While the lesions produced by transmyocardial laser revascularisation (TMLR) induce scar formation, it is important to determine whether this procedure can be deleterious for the left-ventricular function, which is already impaired by the underlying ischaemic process in some patients. Ten channels were drilled in the left lateral wall of the hearts of ten pigs (mean weight, 61 +/- 8.2kg) with a Holmium:YAG laser. Haemodynamic measurements and echocardiographic assessment of left-ventricular function were perfo… Show more

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“…Thirty minutes later, on the other hand, both parameters had normalized, leading Mueller to the conclusion that TMR is a harmless procedure. 14 In a comparative experimental animal study, Kadipasaoglu et al investigated the traumatic impact on myocardium of the three most commonly used lasers: the CO 2 laser, the Ho:YAG laser, and a XeCl Excimer laser. 6 For the CO 2 laser, they measured 520 6 250 mm, exactly the same width of the pericanalicular zone of necrosis as we found in our histological autopsy study.…”
Section: Krabatsch Et Al 256mentioning
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rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…Thirty minutes later, on the other hand, both parameters had normalized, leading Mueller to the conclusion that TMR is a harmless procedure. 14 In a comparative experimental animal study, Kadipasaoglu et al investigated the traumatic impact on myocardium of the three most commonly used lasers: the CO 2 laser, the Ho:YAG laser, and a XeCl Excimer laser. 6 For the CO 2 laser, they measured 520 6 250 mm, exactly the same width of the pericanalicular zone of necrosis as we found in our histological autopsy study.…”
Section: Krabatsch Et Al 256mentioning
“…If we could correct the preconditioning effect, then the flow reduction following TMR might have actually had an even greater and NADH fluorescence might also have become higher. Mueller et al (16) reported that TMR caused a transient drop of ejection fraction and hypokinesis that were reversed within 30 min. Recently, Al-Sheikh et al (1) noted that TMR causes sympathetic denervation relieving angina pain without perfusion improvement and possibly silent ischemia.…”
Section: Discussionmentioning
“…A dúvida decorre de qual seria o número máximo de canais por área, a partir do qual os efeitos de lesão tecidual superariam os benefícios da RTML. Atualmente, a maioria dos cirurgiões prefere realizar um canal a cada centímetro quadrado de superfície miocárdica (37) . Também compartilhamos com esse ponto de vista, tendo ultimamente limitado o número de canais através da RTML.…”
Section: Número De Canaisunclassified