Arch Dermatol
 1931
DOI: 10.1001/archderm.1931.01450010426009
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Acute Dermatitis Due to Opium Preparations

Nelson Heller1
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Cited by 10 publications

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“…Many patients who had positive patch test reactions to opioids presented with a drug eruption and were therefore sensitized through systemic administration (9–17). However, systemic administration after sensitization by topical exposure can also trigger systemic allergic dermatitis with generalized eruptions (2, 3).…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Many patients who had positive patch test reactions to opioids presented with a drug eruption and were therefore sensitized through systemic administration (9–17). However, systemic administration after sensitization by topical exposure can also trigger systemic allergic dermatitis with generalized eruptions (2, 3).…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Comanos in 1882 (14) was the first to describe a case of dermatitis from opium compounds. In the course of the last century, more case reports were published (15, 16). Subcutaneous administration of morphine and hydromorphone can give local intolerance (17) and has caused generalized dermatitis with positive patch tests in case of hydromorphone (18).…”
Section: Literature Review and Discussionmentioning
confidence: 99%
“…Cutaneous drug eruptions from systemic therapeutical use of opioids have been documented by many authors, probably first by Von Essen in 1894 (19). The systemic cutaneous reactions can be divided in four groups: (i) scarlatiniform erythemas (8, 18–23), (ii) eczematous reactions (8–11, 16, 18, 24, 25), (iii) pruritus and urticaria (probably also caused by direct histamine release) (8, 22, 26, 27) and (iv) other drug eruptions like erythema multiforme (11, 28), fixed drug eruptions (29–31) and erythema nodosum (32).…”
Section: Literature Review and Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“… Some examples of literature given; data not specified because of difficulties in assessing very early literature. In this literature, (occupational) contact dermatitis and (in some cases) systemic allergic dermatitis to opium alkaloids, including codeine, morphine, apomorphine, and ethylmorphine have been described (eg, refer 131‐136 ; reviews in refs 131,133 131 …”
Section: Systemic Allergic Dermatitis From Systemic Drugsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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