Acute cerebral venous thrombosis – still underdiagnosed pathology in the emergency computed tomography of the brain

Jacków-Nowicka, Jagoda; Jagiello, J.; Dziadkowiak, Edyta; Bladowska, Joanna; Sąsiadek, Marek; Zimny, Anna

doi:10.5114/pjr.2021.109490

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Parenchymal lesions were assessed using a combination of MRI and CT techniques, including unenhanced CT, T2-weighted imaging (T2-WI), fluid-attenuated inversion recovery (FLAIR), diffusion-weighted imaging (DWI), and apparent diffusion coefficient (ADC) sequences [ 11 , 12 ]. The identified parenchymal changes were then classified into four distinct subgroups: edema, venous infarction, hemorrhage, and mass effect.…”

Section: Methodsmentioning

confidence: 99%

Cortical vein involvement and its influence in a cohort of adolescents with cerebral venous thrombosis

et al. 2023

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Background and purpose Cortical vein thrombosis (CVT) is a rare form of cerebral venous sinus thrombosis (CVST) in adolescent patients that has received little attention. We aimed to analyze the clinical and radiological features of adolescents with CVST and investigate the effects of CVT involvement. Methods Patients aged ≥ 10 to ≤ 18 years and diagnosed with CVST were identified at Xuanwu Hospital, Capital Medical University between January 2015 and August 2022 and divided into two groups according to the presence or absence of cortical vein involvement. Additionally, the patients were also categorized based on their sex. Clinical features, radiological characteristics, and 12-month follow-up outcomes were compared between the two groups. Results Fifty-three adolescents, including 21 with CVT, were included (mean age: 15.2 ± 1.8 years; females, 54.7%). The CVT group was more likely to experience seizures (P = 0.028) and deterioration (28.6% vs. 6.2%, P = 0.047) during hospitalization than the non-CVT group. Poor short-term outcomes, based on the modified Rankin Scale (mRS) score at discharge, were more common in adolescents with CVT (P = 0.007). The proportions of patients showing edema (42.9% vs. 6.2%, P = 0.004) and mass effect (P = 0.015) were significantly higher in the CVT group. Recanalization was observed in 61.9% and 82.1% of the patients in the CVT and non-CVT groups, respectively, during the first imaging review (median, 22 days). After a 12-month follow-up, female adolescents had more frequent resident secondary headaches than male adolescents (52.9% vs. 12.5%; P = 0.014). Conclusions Cortical vein involvement in adolescents with CVST was associated with a higher risk of epilepsy at presentation, deterioration during hospitalization, edema, and mass effect on acute imaging. Moreover, cortical vein involvement may lead to worse short-term outcomes. Sex differences require consideration in etiological analyses and prolonged follow-ups.

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Section: Methodsmentioning

confidence: 99%