Acute Aphasia in Multiple Sclerosis

Acute aphasia in multiple sclerosis

“…In contrast, 5 of the 16 cases reported in the literature had focal seizures documented by EEG studies. 4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia.…”

“…4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia. Only 44% of our patients with Broca aphasia had lesions involving the frontal and/or insular regions (60% in the literature).…”

“…[1][2][3][4][5][6][7] Our study describes the largest cohort to date and found a prevalence of 0.81%, suggesting that this symptom is not as rare in MS as previously thought. Acute aphasia occurring during a relapse of the disease has to be distinguished from chronic language disorders in MS.…”

Acute aphasia in multiple sclerosis

“…In contrast, 5 of the 16 cases reported in the literature had focal seizures documented by EEG studies. 4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia.…”

“…4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia. Only 44% of our patients with Broca aphasia had lesions involving the frontal and/or insular regions (60% in the literature).…”

“…[1][2][3][4][5][6][7] Our study describes the largest cohort to date and found a prevalence of 0.81%, suggesting that this symptom is not as rare in MS as previously thought. Acute aphasia occurring during a relapse of the disease has to be distinguished from chronic language disorders in MS.…”

Comment on “Aphasic or amnesic status epilepticus detected on PET but not EEG”

“…They are generally rhythmic…” (Noachtar et al., 1999). These characteristic rhythmic seizure patterns have been reported in a number of cases of aphasic or amnesic SE caused by a neuroinflammatory disorder (Trinka et al., 2001, 2002), at times similar to patients 1 and 2 of Dong et al. (2009).…”

De novo aphasic status epilepticus as presenting symptom of multiple sclerosis

“…Though MRI can reliably detect white matter lesions in MS, the cortical lesions are yet not fully reproduced by MRI [12]. In previously described patients with status aphasicus a clear correlation between the aphasia, the ictal EEG and the development of a new gadolinium enhancing lesion in the MRI was possible [7,13,14]. Conversely in our patient conventional MRI failed to show such a lesion.…”

Acute aphasia in multiple sclerosis

“…In contrast, 5 of the 16 cases reported in the literature had focal seizures documented by EEG studies. 4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia.…”

“…4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia. Only 44% of our patients with Broca aphasia had lesions involving the frontal and/or insular regions (60% in the literature).…”

“…[1][2][3][4][5][6][7] Our study describes the largest cohort to date and found a prevalence of 0.81%, suggesting that this symptom is not as rare in MS as previously thought. Acute aphasia occurring during a relapse of the disease has to be distinguished from chronic language disorders in MS.…”

Comment on “Aphasic or amnesic status epilepticus detected on PET but not EEG”

“…They are generally rhythmic…” (Noachtar et al., 1999). These characteristic rhythmic seizure patterns have been reported in a number of cases of aphasic or amnesic SE caused by a neuroinflammatory disorder (Trinka et al., 2001, 2002), at times similar to patients 1 and 2 of Dong et al. (2009).…”

De novo aphasic status epilepticus as presenting symptom of multiple sclerosis

“…Though MRI can reliably detect white matter lesions in MS, the cortical lesions are yet not fully reproduced by MRI [12]. In previously described patients with status aphasicus a clear correlation between the aphasia, the ictal EEG and the development of a new gadolinium enhancing lesion in the MRI was possible [7,13,14]. Conversely in our patient conventional MRI failed to show such a lesion.…”

Acute aphasia in multiple sclerosis

“…In contrast, 5 of the 16 cases reported in the literature had focal seizures documented by EEG studies. 4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia.…”

“…4 Nevertheless, the clinical features of these five patients were quite different from those of our patients: All but one experienced repeated episodes of language impairment (transient or prolonged). 4 Some of the clinical-radiologic correlations in our study do not fit classic data in vascular aphasiology, especially in Broca aphasia. Only 44% of our patients with Broca aphasia had lesions involving the frontal and/or insular regions (60% in the literature).…”

“…[1][2][3][4][5][6][7] Our study describes the largest cohort to date and found a prevalence of 0.81%, suggesting that this symptom is not as rare in MS as previously thought. Acute aphasia occurring during a relapse of the disease has to be distinguished from chronic language disorders in MS.…”

Comment on “Aphasic or amnesic status epilepticus detected on PET but not EEG”

“…They are generally rhythmic…” (Noachtar et al., 1999). These characteristic rhythmic seizure patterns have been reported in a number of cases of aphasic or amnesic SE caused by a neuroinflammatory disorder (Trinka et al., 2001, 2002), at times similar to patients 1 and 2 of Dong et al. (2009).…”

De novo aphasic status epilepticus as presenting symptom of multiple sclerosis

“…Though MRI can reliably detect white matter lesions in MS, the cortical lesions are yet not fully reproduced by MRI [12]. In previously described patients with status aphasicus a clear correlation between the aphasia, the ictal EEG and the development of a new gadolinium enhancing lesion in the MRI was possible [7,13,14]. Conversely in our patient conventional MRI failed to show such a lesion.…”