Acute Annular Outer Retinopathy

Acute Annular Outer Retinopathy: Literature Review and a Report of 2 Cases

“…However, in the report by Rodriguez-Coleman and colleagues, 8 the disease progressed despite this treatment. Similarly, in the case presented by Cheung and colleagues, 7 oral prednisone and acyclovir were initiated; however, no visual improvement was achieved.…”

“…Testing with electrodiagnostics was reported in 13 cases (65.0%.) 1,6 -15 The ERG was found to be abnormal in 11 of these cases (84.6%.) 6,8 A predominant loss of cone-mediated ERG responses has been reported, as well as a predominant loss of rod-mediated ERG responses.…”

“…In at least 6 cases (30.0%), the retinal whitening resolved by 6 weeks or sooner. 1,7,10,11,14,15 In contrast, 1 case showed progression over more than 14 months. 13 In 11 cases (55.0%) that showed long-term follow-up, including Case 1 from this report, there was some degree of RPE mottling, pigmentary migration, or atrophy noted with the resolution of the retinal whitening.…”

“…In 18 cases (90.0%), including the 2 from our work, FA was reported. 1,2,5 -12,14,15 In 7 (38.9%) of these, the whitish-gray annular retinal change seen clinically appeared unremarkable on FA. 1,2,5,6,11,12 In 3 (16.7%) of these cases, the overall angiogram was normal early in the disease, 11,12,15 while in another 2 cases (11.1%), delayed dye transit in the involved quadrant was observed.…”

“…In the other 11 cases (61.1%), including the 2 presented in this report, the area of the affected retina appeared hyperfluorescent on FA. 6 -11,14 Four (22.2%) of these reported a hypofluorescent ring at the edge of the affected retina. 6 -9…”

Acute Annular Outer Retinopathy: Literature Review and a Report of 2 Cases

“…However, in the report by Rodriguez-Coleman and colleagues, 8 the disease progressed despite this treatment. Similarly, in the case presented by Cheung and colleagues, 7 oral prednisone and acyclovir were initiated; however, no visual improvement was achieved.…”

“…Testing with electrodiagnostics was reported in 13 cases (65.0%.) 1,6 -15 The ERG was found to be abnormal in 11 of these cases (84.6%.) 6,8 A predominant loss of cone-mediated ERG responses has been reported, as well as a predominant loss of rod-mediated ERG responses.…”

“…In at least 6 cases (30.0%), the retinal whitening resolved by 6 weeks or sooner. 1,7,10,11,14,15 In contrast, 1 case showed progression over more than 14 months. 13 In 11 cases (55.0%) that showed long-term follow-up, including Case 1 from this report, there was some degree of RPE mottling, pigmentary migration, or atrophy noted with the resolution of the retinal whitening.…”

“…In 18 cases (90.0%), including the 2 from our work, FA was reported. 1,2,5 -12,14,15 In 7 (38.9%) of these, the whitish-gray annular retinal change seen clinically appeared unremarkable on FA. 1,2,5,6,11,12 In 3 (16.7%) of these cases, the overall angiogram was normal early in the disease, 11,12,15 while in another 2 cases (11.1%), delayed dye transit in the involved quadrant was observed.…”

“…In the other 11 cases (61.1%), including the 2 presented in this report, the area of the affected retina appeared hyperfluorescent on FA. 6 -11,14 Four (22.2%) of these reported a hypofluorescent ring at the edge of the affected retina. 6 -9…”

Acute Annular Outer Retinopathy: Literature Review and a Report of 2 Cases

“…However, in the report by Rodriguez-Coleman and colleagues, 8 the disease progressed despite this treatment. Similarly, in the case presented by Cheung and colleagues, 7 oral prednisone and acyclovir were initiated; however, no visual improvement was achieved.…”

“…Testing with electrodiagnostics was reported in 13 cases (65.0%.) 1,6 -15 The ERG was found to be abnormal in 11 of these cases (84.6%.) 6,8 A predominant loss of cone-mediated ERG responses has been reported, as well as a predominant loss of rod-mediated ERG responses.…”

“…In at least 6 cases (30.0%), the retinal whitening resolved by 6 weeks or sooner. 1,7,10,11,14,15 In contrast, 1 case showed progression over more than 14 months. 13 In 11 cases (55.0%) that showed long-term follow-up, including Case 1 from this report, there was some degree of RPE mottling, pigmentary migration, or atrophy noted with the resolution of the retinal whitening.…”

“…In 18 cases (90.0%), including the 2 from our work, FA was reported. 1,2,5 -12,14,15 In 7 (38.9%) of these, the whitish-gray annular retinal change seen clinically appeared unremarkable on FA. 1,2,5,6,11,12 In 3 (16.7%) of these cases, the overall angiogram was normal early in the disease, 11,12,15 while in another 2 cases (11.1%), delayed dye transit in the involved quadrant was observed.…”

“…In the other 11 cases (61.1%), including the 2 presented in this report, the area of the affected retina appeared hyperfluorescent on FA. 6 -11,14 Four (22.2%) of these reported a hypofluorescent ring at the edge of the affected retina. 6 -9…”

Acute Annular Outer Retinopathy: Literature Review and a Report of 2 Cases

“…However, in the report by Rodriguez-Coleman and colleagues, 8 the disease progressed despite this treatment. Similarly, in the case presented by Cheung and colleagues, 7 oral prednisone and acyclovir were initiated; however, no visual improvement was achieved.…”

“…Testing with electrodiagnostics was reported in 13 cases (65.0%.) 1,6 -15 The ERG was found to be abnormal in 11 of these cases (84.6%.) 6,8 A predominant loss of cone-mediated ERG responses has been reported, as well as a predominant loss of rod-mediated ERG responses.…”

“…In at least 6 cases (30.0%), the retinal whitening resolved by 6 weeks or sooner. 1,7,10,11,14,15 In contrast, 1 case showed progression over more than 14 months. 13 In 11 cases (55.0%) that showed long-term follow-up, including Case 1 from this report, there was some degree of RPE mottling, pigmentary migration, or atrophy noted with the resolution of the retinal whitening.…”

“…In 18 cases (90.0%), including the 2 from our work, FA was reported. 1,2,5 -12,14,15 In 7 (38.9%) of these, the whitish-gray annular retinal change seen clinically appeared unremarkable on FA. 1,2,5,6,11,12 In 3 (16.7%) of these cases, the overall angiogram was normal early in the disease, 11,12,15 while in another 2 cases (11.1%), delayed dye transit in the involved quadrant was observed.…”

“…In the other 11 cases (61.1%), including the 2 presented in this report, the area of the affected retina appeared hyperfluorescent on FA. 6 -11,14 Four (22.2%) of these reported a hypofluorescent ring at the edge of the affected retina. 6 -9…”