Activity of Sphingomyelinase in Rat Liver in Acute and Chronic Toxic Hepatitis: Proportion between Peroxidative and Phospholipase Pathways of Lipid Bilayer Modification

Abstract

We showed that sphingomyelinase activity in the liver increased only during the acute phase of toxic hepatitis. Peroxidative modification of hepatocyte membrane bilayer prevailed during the acute phase, while after transformation of the process to the chronic phase phospholipase pathway predominated.