Activités antioxydante, apoptotique et antiproliférative de Tetraena gaetula (Emb. &amp; Maire) Beier &amp; Thulin et de Berberis hispanica Boiss. &amp; Reut. originaires du Maroc

Youbi, Amal El Hamsas El; Bousta, Dalila; Jamoussi, B.; Greche, H.; Mansouri, Latifa El; Benjilali, J.; Soidrou, S. H.

doi:10.1007/s10298-012-0704-3

Cited by 9 publications

(3 citation statements)

References 43 publications

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“…These results agree with those reported in the literature, which showed that genus Berberis contained tamarixetin, rutin, and caffeic acid, all known for their cytotoxic effects against cancer cell lines including HeLa cells with IC 50 > 100 µg/mL. Moreover, the alkaloid extract from indigenous species to Algeria induced cell death and morphological changes [13,19].…”

Section: In Vitro Antiproliferative Activity Assaysupporting

confidence: 92%

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Antioxidant and Understanding the Anticancer Properties in Human Prostate and Breast Cancer Cell Lines of Chemically Characterized Methanol Extract from Berberis hispanica Boiss. & Reut

et al. 2021

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The current research was conducted to investigate the chemical profile, antiproliferative, and antioxidant activities of methanol extracts obtained by two different methods including maceration and Soxhlet from Berberis hispanica Boiss. & Reut. Antiproliferative activities were evaluated by the MTT (3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) assay in four human cancer cell lines including prostate (LnCap and 22 RV1) and breast cancer (MDA-MB-231 and MCF7). The antioxidant power was evaluated by DPPH ((2,2-diphenyl-1-picryl-hydrazyl-hydrate), ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), and FRAPS (Ferric reducing antioxidant power) tests. The chemical composition was conducted by gas chromatography-mass spectrometry (GC-MS) after methylation. Total phenolic and flavonoid contents were assessed using the Folin–Ciocalteu method. The phytochemical analysis showed that the tested extracts possessed inserting potentially active compounds. The MTT test revealed that both extracts (maceration and Soxhlet) reduced cell viability in all cell lines tested. In breast cancer cell lines MDA-MB-231 and MCF-7, the IC50 values obtained by maceration were 16.55 ± 0.58 and 17.95 ± 0.58 µg/mL, respectively. These values were slightly lower than those obtained with the Soxhlet extract toward MDA-MB-231 (19.93 ± 0.74 µg/mL) and MCF-7 (20.22 ± 0.89 µg/mL). Regarding prostate cancer cells 22 RV and LnCap, the IC50 values obtained by maceration extract (22 RV: 11.75 ± 0.35 µg/mL; LnCap: 11.91 ± 0.54 µg/mL) were also slightly lower than those obtained with Soxhlet (22 RV: 13.47 ± 0.52 µg/mL; LnCap: 19.64 ± 1.05 µg/mL). The antioxidant activity showed that the studied extracts had considerable antioxidant activity (DPPH, FRAP, and ABTS) with particular attention to the extract obtained with maceration. The Berberis hispanica Bois. and Reut. can serve society as it provides potentially bioactive compounds that may find application in the medical sector to control such diseases.

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Section: In Vitro Antiproliferative Activity Assaysupporting

confidence: 92%

“…However, the available results on its chemical composition are more limited [10,12]. These compounds are responsible for Berberis biological activities such as antidepressant, antinociceptive, and immunomodulation effects [11,13].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and Understanding the Anticancer Properties in Human Prostate and Breast Cancer Cell Lines of Chemically Characterized Methanol Extract from Berberis hispanica Boiss. & Reut

et al. 2021

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“…The antioxidant activity of the networks and the monomers was determined according to the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. − Thirty milligrams of the network or the monomer glutathione was immersed in 3 mL of 0.1 mM DPPH solution (in methanol). This solution was then left in the dark for 1 h at room temperature.…”

Section: Experimental Sectionmentioning

confidence: 99%

Enhancement of Biological Properties of Photoinduced Biobased Networks by Post-Functionalization with Antibacterial Molecule

Modjinou

Versace

Abbad-Andaloussi

et al. 2018

ACS Sustainable Chem. Eng.

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Biobased post-functionalized networks were designed by photoinduced cationic reaction using a biheterofunctional eugenol derivative. The originality of this study is to mobilize the carbon double bond of this compound which did not react during the formation of the networks so as to graft molecules of interest to the surface of the materials (here an antibacterial agent). The photoactivated thiol–ene reaction was chosen for the post-functionalization since this chemical route is nowadays considered a green process and leads to fast kinetics and high conversions. Different networks were prepared by varying the proportion of carbon double bond and consequently the proportion of antibacterial compound grafted into the resulting material. The thermo-mechanical performances and the biological activity were strongly investigated before and after the post-functionalization process.

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Recent Advances in Bioactivities of Common Food Biocompounactives

Guaâdaoui

2017

Fruit and Vegetable Phytochemicals

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Activités antioxydante, apoptotique et antiproliférative de Tetraena gaetula (Emb. & Maire) Beier & Thulin et de Berberis hispanica Boiss. & Reut. originaires du Maroc

Cited by 9 publications

References 43 publications

Antioxidant and Understanding the Anticancer Properties in Human Prostate and Breast Cancer Cell Lines of Chemically Characterized Methanol Extract from Berberis hispanica Boiss. & Reut

Antioxidant and Understanding the Anticancer Properties in Human Prostate and Breast Cancer Cell Lines of Chemically Characterized Methanol Extract from Berberis hispanica Boiss. & Reut

Enhancement of Biological Properties of Photoinduced Biobased Networks by Post-Functionalization with Antibacterial Molecule

Recent Advances in Bioactivities of Common Food Biocompounactives

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