volume 66, issue 9, P5479-5484 1992
DOI: 10.1128/jvi.66.9.5479-5484.1992
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Abstract: Human immunodeficiency virus type 2 (HIV-2) displays several features which distinguish it from HIV-1. Among the differences in these two viruses are the responses of their enhancer regions to T-cell activation. For example, stimulation of HIV-1 transcription is largely dependent on two KB regulatory elements. In contrast, the HIV-2 enhancer has a single KB site and contains additional cis-acting sequences responsive to induction. One of these sites, previously termed CD3R, is a purine-rich site, also called P…

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