Acremonium falciforme (Cephalosporium falciforme) mycetoma in a renal transplant patient

Etta, Linda L. Van

doi:10.1001/archderm.119.8.707

Cited by 12 publications

(10 citation statements)

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“…c Location undetermined means that it was not possible to track the origin of the samples from which those fungi were obtained. falciforme is emerging as an agent of infections (Van Etta et al, 1983;Miró et al, 1994;Lau et al, 1995;Noble et al, 1997), thus overlapping more broadly in pathogenic potential with Fusarium solani. Fusarium ketatoplasticum and F. falciforme are capable of causing disease on sea turtle eggs and further studies on prevalence of both species and the potential impact of this prevalence on nesting populations are necessary.…”

Section: Discussionmentioning

confidence: 99%

Isolation of fungal pathogens from eggs of the endangered sea turtle speciesChelonia mydasin Ascension Island

et al. 2016

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Fungal emerging pathogens are one of the main threats for global biodiversity. Sea turtles do not seem to be an exemption, and recent studies on important nesting areas worldwide have shown that two fungal pathogens, i.e. Fusarium falciforme and Fusarium keratoplasticum, are involved in low hatching success in nests of sea turtle species. Although the presence of these pathogens has been detected in Ascension Island, there are no investigations on the distribution of these two pathogens in main nesting beaches in the island. In this study, we analysed 109 eggshells of the species Chelonia mydas from four nesting areas in Ascension Island. We have isolated and identified a total of 46 fungal isolates. A phylogenetic analysis, of the ITS nrDNA region, with a number of reference sequences of the Fusarium solani species complex, showed that 23 of these isolates corresponded to the pathogen F. keratoplasticum. The analyses on isolation frequency, that included other previously obtained isolates, i.e. 11 F. keratoplasticum and one F. falciforme, showed that F. keratoplasticum was the species most frequently isolated in Ascension Island and it was found in all nesting beaches, while F. falciforme was only isolated from Pan Am beach. When compared with other nesting areas worldwide, the abundance of F. keratoplasticum over F. falciforme was higher than any other nesting region tested. These findings are important in order to evaluate the potential threat of this pathogen to nests of the sea turtle population of Ascension Island, and to develop future control strategies.

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Section: Discussionmentioning

confidence: 99%

Isolation of fungal pathogens from eggs of the endangered sea turtle speciesChelonia mydasin Ascension Island

et al. 2016

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“…Using a literature search, 20 evaluable cases of eumycetoma caused by Fusarium species were retrieved and included in our analysis from 1964 till 2016, 15,[17][18][19][20][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] (Table 1), while three articles could not be acquired. 14,42,43 Cases were reported from the following continents:…”

Section: Types Of Articlesmentioning

confidence: 99%

Fusarium species causing eumycetoma: Report of two cases and comprehensive review of the literature

Al‐Hatmi

Bonifáz

Tirado‐Sánchez

et al. 2016

Mycoses

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Recently, mycetoma was added to the World Health Organization's list of neglected tropical disease priorities. Fusarium as a genus has been reported to cause eumycetoma, but little is known about the species involved in this infection and their identification. In this study, molecular tools were applied to identify Fusarium agents from human eumycetoma cases. The partial translation elongation factor 1-alpha (TEF-1α) gene was used as diagnostic parameter. Two additional cases of eumycetoma, due to F. keratoplasticum and F. pseudensiforme, respectively, are presented. A systematic literature review was performed to assess general features, identification, treatment and outcome of eumycetoma infections due to Fusarium species. Of the 20 reviewed patients, the majority (75%) were male. Most agents belonged to the F. solani species complex, ie F. keratoplasticum, F. pseudensiforme, and an undescribed lineage of F. solani. In addition, F. thapsinum, a member of Fusarium fujikuroi species complex was encountered. The main antifungal drugs used were itraconazole, ketoconazole and amphotericin B, but cure rates were low (15%). Partial response or relapse was observed in some cases, and a case ended in amputation. Clinical management of eumycetoma due to Fusarium is complex and combination therapy might be required to increase cure rates.

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“…While F. solani is not principally thought of as a cause of mycetoma, it has been reported from at least four such cases worldwide (18); the United Kingdom National Collection of Pathogenic Fungi contains isolates from patients with additional confirmed cases (18). In recent years, there has been evidence that F. falciforme is emerging as an agent of localized (28,36,56) and disseminated (39) infections in immunocompromised patients, thus overlapping more broadly in pathogenic potential with F. solani. An F. falciforme endophthalmitis has also been documented (4).…”

Section: Fig 1 Phylogenetic Relationships Within the Genusmentioning

confidence: 99%

Analysis of Phylogenetic Relationship of Cylindrocarpon lichenicola and Acremonium falciforme to the Fusarium solani Species Complex and a Review of Similarities in the Spectrum of Opportunistic Infections Caused by These Fungi

Summerbell

Schroers

2002

J Clin Microbiol

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Acremonium falciforme (Cephalosporium falciforme) mycetoma in a renal transplant patient

Cited by 12 publications

References 0 publications

Isolation of fungal pathogens from eggs of the endangered sea turtle speciesChelonia mydasin Ascension Island

Isolation of fungal pathogens from eggs of the endangered sea turtle speciesChelonia mydasin Ascension Island

Fusarium species causing eumycetoma: Report of two cases and comprehensive review of the literature

Analysis of Phylogenetic Relationship of Cylindrocarpon lichenicola and Acremonium falciforme to the Fusarium solani Species Complex and a Review of Similarities in the Spectrum of Opportunistic Infections Caused by These Fungi

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