Acquired Immune Deficiency Syndrome

Holland, Gary N.; Pepose, Jay S.; Pettit, Thomas H.; Gottlieb, Michael; Yee, Robert D.; Foos, Robert Y.

doi:10.1016/s0161-6420(83)80009-8

Cited by 468 publications

(80 citation statements)

References 31 publications

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“…[25] According to various studies ocular lesions occur in 40-70% of the AIDS patients. [26,27,28] The male preponderance of the study subjects in the current study may be because of their increased risk behaviour compared to females in the study area.…”

Section: Discussionmentioning

confidence: 82%

A Study of Ocular Complications of HIV/AIDS in a Teaching Medical College in North-Eastern India

Singh¹,

Singh²

2018

AIMDR

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Background: HIV infection/AIDS is becoming a public health hazard globally. Ocular complications of HIV/AIDS are very common and its severity increases as the disease progresses and ultimately leads to blindness. Objective: The purpose of the present study was to determine the prevalence and type of ocular complications in patients with HIV/AIDS. Methods: A cross-sectional study was done on patients with HIV infection/AIDS who attended or referred to eye OPD and also cases from General Medicine ward of JNIMS. A complete ophthalmic evaluation of both anterior and posterior segments was conducted. HIV sero-positivity was established by ELISA and confirmed by Western Blot in all cases. Results: The majority of the patients were in the age group of 21-40yrs. The prevalence of ocular involvement was 47%. The commonest involvement was on posterior segment with HIV retinopathy and cotton wool spots (20%) and CMV retinitis (5%). Anterior segment involvement was 18% with conjunctival micro-vasculopathy being the commonest (8%) and HZO in 5 cases. Conclusion: HIV infection is fairly common in Manipur among the age group of 20-40yrs., IDU being the commonest route of infection. Ocular involvement occurred in 47% of cases and it may be the first manifestation. So, the ophthalmologist must be aware for prompt treatment and prevention of visual disabilities.

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Section: Discussionmentioning

confidence: 82%

A Study of Ocular Complications of HIV/AIDS in a Teaching Medical College in North-Eastern India

Singh¹,

Singh²

2018

AIMDR

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“…One of these possible agents could include atypical mycobacteria (19) . Some authors postulated that atypical mycobacteria or Mycobacterium avium intracellulare could produce a subclinical systemic infection that would cause a choroiditis leaving choroidal scars (19)(20)(21) . In conclusion, clinical findings of ocular histoplasmosis were described in non-histoplasmosis patients.…”

Section: Discussionmentioning

confidence: 99%

Ocular histoplasmosis-like syndrome: a report from a nonendemic area

Amaro¹,

Muccioli²,

Abreu³

2007

Arq. Bras. Oftalmol.

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“…There is no mention of tuberculosis in the early landmark reports on ocular features of HIV/AIDS because it was not encountered clinically, 52,53 and reviews gave tuberculosis negligible attention. 54 The collective clinical memory of the diagnostic value of the choroidal tubercle was lost over a gap of more than two generations.…”

Section: Personal Viewmentioning

confidence: 99%

“…71 A study from Myanmar reported that a third of patients diagnosed with cytomegalovirus retinitis on eye screening and given only local intraocular ganciclovir failed to survive 3 months. 72 Cotton wool spots, present in 15-50% of patients with low CD4 counts, [52][53][54] are strongly associated with high HIV viral load. 73 They resolve quickly with ART, and might be clinically helpful for monitoring response to ART in settings without access to viral load testing, identifying patients who are non-adherent.…”

Section: Personal Viewmentioning

confidence: 99%